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Role of Toll-Like Receptor 5 in the Development of Ulcerative Colitis [PDF]

open access: yesArchives of Razi Institute, 2021
Inflammatory bowel disease (ulcerative colitis and Crohn’s disease) is a remitting and relapsing disease that affects millions of people worldwide. In the intestine, homeostasis between repair and signaling of the proinflammatory of the immune system is ...
A Falah Alshimerry   +2 more
doaj   +1 more source

Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.

open access: yesNew England Journal of Medicine, 2021
BACKGROUND Ozanimod, a selective sphingosine-1-phosphate receptor modulator, is under investigation for the treatment of inflammatory bowel disease. METHODS We conducted a phase 3, multicenter, randomized, double-blind, placebo-controlled trial of ...
W. Sandborn   +15 more
semanticscholar   +1 more source

The LUCID study: living with ulcerative colitis; identifying the socioeconomic burden in Europe

open access: yesBMC Gastroenterology, 2021
Background Ulcerative colitis (UC) is an inflammatory bowel disease with increasing prevalence worldwide. Current treatment strategies place considerable economic and humanistic burdens on patients.
Leonardo Ruiz-Casas   +14 more
doaj   +1 more source

Modern principles of conservative treatment of mild and moderate forms of ulcerative colitis

open access: yesЛечащий Врач, 2022
Ulcerative colitis is a chronic disease characterized by inflammation that usually begins in the rectum and diffusely spreads proximally, involving part or all of the colonic mucosa.
O. V. Golovenko
doaj   +1 more source

Ozanimod: A Review in Ulcerative Colitis

open access: yesDrugs, 2022
Ozanimod (Zeposia®) is the first sphingosine-1-phosphate receptor (S1PR) modulator to be approved for the treatment of adults with moderately to severely active ulcerative colitis in the USA, and in adults with moderately to severely active ulcerative ...
J. Paik
semanticscholar   +1 more source

Multi-factor mediated functional modules identify novel classification of ulcerative colitis and functional gene panel

open access: yesScientific Reports, 2021
Ulcerative colitis is a chronic, idiopathic, and inflammatory disease of the rectal and colonic mucosa, the behavior of which is of heterogeneity in individuals.
Lijie Lai   +4 more
doaj   +1 more source

Atherosclerotic Cardiovascular Disease in Inflammatory Bowel Disease: The Role of Chronic Inflammation and Platelet Aggregation

open access: yesMedicina, 2023
Background and Objectives: Atherosclerosis is one of inflammatory bowel disease’s most significant cardiovascular manifestations. This research aimed to examine the relationship between biochemical, haemostatic, and immune parameters of atherosclerosis ...
Sofija I. Lugonja   +9 more
doaj   +1 more source

Oral manifestation of ulcerative colitis [PDF]

open access: yesStomatološki glasnik Srbije, 2022
Introduction Ulcerative colitis is an inflammatory bowel disease. Primary involvement is the colon. Changes in the oral cavity may occur as the part of extraintestinal manifestations of the disease.
Đuričković Aleksa   +1 more
doaj   +1 more source

Ulcerative colitis: an update.

open access: yesClinical medicine (London), 2021
Ulcerative colitis is a relapsing and remitting disease that is increasing in incidence and prevalence. Management aims to achieve rapid resolution of symptoms, mucosal healing and improvement in a patient's quality of life.
J. Segal, J. LeBlanc, A. Hart
semanticscholar   +1 more source

Serum antibodies in first-degree relatives of patients with IBD: A marker of disease susceptibility? A follow-up pilot-study after 7 years [PDF]

open access: yes, 2005
Introduction: Various disease-specific serum antibodies were described in patients with inflammatory bowel disease and their yet healthy first-degree relatives.
Bansi DS   +29 more
core   +5 more sources

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