Results 1 to 10 of about 467,445 (327)

Integrated bioinformatics and network pharmacology to identify the therapeutic target and molecular mechanisms of Huangqin decoction on ulcerative Colitis

Scientific Reports, 2022
Huangqin decoction (HQD) is a Traditional Chinese Medicine formula for ulcerative colitis. However, the pharmacology and molecular mechanism of HQD on ulcerative colitis is still unclear.
Yi Wu, Xinqiao Liu, Guiwei Li
doaj   +2 more sources

Role of Toll-Like Receptor 5 in the Development of Ulcerative Colitis [PDF]

Archives of Razi Institute, 2021
Inflammatory bowel disease (ulcerative colitis and Crohn’s disease) is a remitting and relapsing disease that affects millions of people worldwide. In the intestine, homeostasis between repair and signaling of the proinflammatory of the immune system is ...
A Falah Alshimerry, R Ghalib Farhood, H Hasan Shakir   +2 more
doaj   +1 more source

The LUCID study: living with ulcerative colitis; identifying the socioeconomic burden in Europe

BMC Gastroenterology, 2021
Background Ulcerative colitis (UC) is an inflammatory bowel disease with increasing prevalence worldwide. Current treatment strategies place considerable economic and humanistic burdens on patients.
Leonardo Ruiz-Casas, Jonathan Evans, Alison Rose, Gabriel Ghizzi Pedra, Alan Lobo, Alan Finnegan, Bu Hayee, Laurent Peyrin-Biroulet, Andreas Sturm, Johan Burisch, Helen Terry, Luisa Avendano, Seb Tucknott, Gionata Fiorino, Jimmy Limdi   +14 more
doaj   +1 more source

Modern principles of conservative treatment of mild and moderate forms of ulcerative colitis

Лечащий Врач, 2022
Ulcerative colitis is a chronic disease characterized by inflammation that usually begins in the rectum and diffusely spreads proximally, involving part or all of the colonic mucosa.
O. V. Golovenko
doaj   +1 more source

Ozanimod as Induction and Maintenance Therapy for Ulcerative Colitis.

New England Journal of Medicine, 2021
BACKGROUND Ozanimod, a selective sphingosine-1-phosphate receptor modulator, is under investigation for the treatment of inflammatory bowel disease. METHODS We conducted a phase 3, multicenter, randomized, double-blind, placebo-controlled trial of ...
W. Sandborn, B. Feagan, G. D'Haens, D. Wolf, I. Jovanović, S. Hanauer, Subrata Ghosh, A. Petersen, S. Hua, Ji Hwan Lee, L. Charles, D. Chitkara, K. Usiskin, J. Colombel, L. Laine, S. Danese   +15 more
semanticscholar   +1 more source

Multi-factor mediated functional modules identify novel classification of ulcerative colitis and functional gene panel

Scientific Reports, 2021
Ulcerative colitis is a chronic, idiopathic, and inflammatory disease of the rectal and colonic mucosa, the behavior of which is of heterogeneity in individuals.
Lijie Lai, Hanyang Li, Qi Feng, Jun Shen, Zhihua Ran   +4 more
doaj   +1 more source

Oral manifestation of ulcerative colitis [PDF]

Stomatološki glasnik Srbije, 2022
Introduction Ulcerative colitis is an inflammatory bowel disease. Primary involvement is the colon. Changes in the oral cavity may occur as the part of extraintestinal manifestations of the disease.
Đuričković Aleksa, Đuričković Mirjana   +1 more
doaj   +1 more source

Cholesterol sulfate alleviates ulcerative colitis by promoting cholesterol biosynthesis in colonic epithelial cells

Nature Communications, 2022
Cholesterol sulfate, produced by hydroxysteroid sulfotransferase 2B1 (SULT2B1), is highly abundant in the intestine. Herein, we study the functional role and underlying intestinal epithelial repair mechanisms of cholesterol sulfate in ulcerative colitis.
Dongke Xu, Ruijun Ma, Yi Ju, Xiaowei Song, Baolin Niu, Wenting Hong, Rong Wang, Qin Yang, Zhiwei Zhao, Yuchen Zhang, Yufan Zheng, Q. Bai, Mingfang Lv, Ning Sun, Xiaobo Li   +14 more
semanticscholar   +1 more source

Ozanimod: A Review in Ulcerative Colitis

Drugs, 2022
Ozanimod (Zeposia®) is the first sphingosine-1-phosphate receptor (S1PR) modulator to be approved for the treatment of adults with moderately to severely active ulcerative colitis in the USA, and in adults with moderately to severely active ulcerative ...
J. Paik
semanticscholar   +1 more source

Atherosclerotic Cardiovascular Disease in Inflammatory Bowel Disease: The Role of Chronic Inflammation and Platelet Aggregation

Medicina, 2023
Background and Objectives: Atherosclerosis is one of inflammatory bowel disease’s most significant cardiovascular manifestations. This research aimed to examine the relationship between biochemical, haemostatic, and immune parameters of atherosclerosis ...
Sofija I. Lugonja, Ivana L. Pantic, Tamara M. Milovanovic, Vesna M. Grbovic, Bojana M. Djokovic, Željko D. Todorovic, Stefan M. Simovic, Raša H. Medovic, Nebojsa D. Zdravkovic, Natasa D. Zdravkovic   +9 more
doaj   +1 more source