Results 161 to 170 of about 213,127 (265)

Plasmonic Heterojunction Nanomaterials for Noninvasive Pan‐Cancer Metabolomic Screening

Interdisciplinary Materials, EarlyView.
This study develops gold nanoparticle‐modified manganese–cobalt oxide heterjunctions (Au/MCOM) as a laser desorption/ionization mass spectrometry (LDI‐MS) matrix for acquiring serum metabolic fingerprints. Combined with machine learning, the platform achieves accurate detection and early screening across six cancer types, demonstrating strong potential
Jia Qi, Hairu Lin, Caiyun Fang, Jia Li, Fangying Shi, Chunhui Deng   +5 more
wiley   +1 more source

Gegen Qinlian decoction ameliorates experimental colitis in miceferroptosis pathway. [PDF]

J Tradit Chin Med
Jinke H, Jiaqi Z, Zhihong L, Jing MA, Fengyun W, Xudong T.   +5 more
europepmc   +1 more source

Inverse association between obesity and intestinal endometriosis: Findings from a cross‐sectional study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study evaluates the association between obesity and the presence of bowel endometriosis in patients undergoing surgery. Methods A retrospective cross‐sectional observational study was conducted with patients treated between September 2023 and December 2024, at a specialized endometriosis outpatient clinic of a tertiary hospital ...
Tereza Carolina Fonseca Corrêa, Marco Aurelio Pinho Oliveira   +1 more
wiley   +1 more source

Combined treatment with naringin and osthole ameliorates colitis through microbiota-amino acid metabolism and the JNK pathway. [PDF]

Nat Prod Bioprospect
Chen M, Lu Z, Zhang T, Li G, Zheng Q, Zhang T.   +5 more
europepmc   +1 more source

Targeting Microbiome Metabolites: Reshaping Immunotherapy and Clinical Management Strategies for Colorectal Cancer

iMetaMed, EarlyView.
The occurrence and progression of colorectal cancer are intricately linked to metabolites produced by the gut microbiota. Metabolites generated by pathogenic microbial communities can promote colorectal cancer development by reshaping the immune microenvironment.
Xinrui Yang, Ke Zhang, Lijie Xia, Jinyao Li   +3 more
wiley   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Correction to "DNA Methylation of miR-122 Aggravates Oxidative Stress in Colitis Targeting SELENBP1 Partially by p65NF-κB Signaling". [PDF]

Oxid Med Cell Longev
europepmc   +1 more source

Autoantibodies as predictors for immune-related adverse events in checkpoint inhibition therapy of metastatic melanoma. [PDF]

J Immunother Cancer
Reschke R, Budde P, Zucht HD, Mangana J, Dummer R, Pfoehler C, Wistuba-Hamprecht K, Weide B, Hakim-Meibodi LE, Meier F, Schulz C, Richter J, Bräutigam M, Gutjahr C, Schulz-Knappe P, Hassel JC.   +15 more
europepmc   +1 more source

Oral proton‐reprogrammed nanomedicine to break the inflammatory bowel disease‐Clostridium difficile infection vicious cycle

iMeta, EarlyView.
Research on the mechanism of OPR restoring intestinal epithelial cell (IEC) structure and function in inflammatory bowel disease (IBD) treatment. (A) Schematic diagram of OPR structure and the rate of GP release under different conditions. (B) Schematic diagram of OPR targeting IBD colonic lesions through charge interaction.
Wensheng Chen, Yuntao Zhang, Jue Wang, Yiming Li, Hao Wu, Qiong Huang, Wei Wu, Kelong Ai   +7 more
wiley   +1 more source

Late-Onset Mesalazine-Induced Eosinophilic Pneumonitis Presenting as Non-Resolving Pneumonia: A Diagnostic Pitfall in Ulcerative Colitis. [PDF]

Clin Case Rep
Nasim S, Zaalouk TM, Bocus A, Kerols M.
europepmc   +1 more source