Results 151 to 160 of about 221,136 (217)

Incidence Trends of Early‐Onset Colorectal Cancer in Germany: A Registry‐Based Study From 2003 to 2023

International Journal of Cancer, EarlyView.
The evidence on the rising incidence of colorectal cancer among adults below 50 years of age largely stems from the United States. Using high‐quality cancer registry data for the 2003–2023 period in Germany, this study found a moderate increase of early‐onset colorectal cancer incidence that was limited to those aged 20–39 years and more pronounced ...
Sven Voigtländer, Hiltraud Kajüter, Ina Wellmann, Andras Szentkirályi, Bernd Holleczek, Volker Arndt, Jacqueline Müller‐Nordhorn, the ALSTER Working Group, Josephine Kanbach, Sabine Luttmann, Meike Ressing, Cécile Ronckers, Soo‐Zin Kim‐Wanner, Alice Nennecke, Frederik Peters, Klaus Kraywinkel, Roxana Müller‐Eberstein, Hannah Baltus, Paula Grieger, Antje Schliemann, Annika Waldmann   +20 more
wiley   +1 more source

Correction to:NMI Promotes Pro-Inflammatory Macrophage Polarization and Exacerbates Ulcerative Colitis. [PDF]

Inflammation
Yang H, Wang J, Xu N, Guo X, Weng Z, Song J, Chen Z, Zhang M, Gao Y, Zhao X, Yao Y, You Y, Tang C, Liu Y, Lan P, Liang H.   +15 more
europepmc   +1 more source

Diabetes Increases Immunotherapy‐Related Toxicity but Not Efficacy in Metastatic Non‐Small Cell Lung Cancer: A Multicenter Retrospective Study

International Journal of Cancer, EarlyView.
ABSTRACT This multicenter retrospective study evaluated the impact of type 2 diabetes mellitus (DM) on clinical outcomes and immune‐related adverse events (irAEs) in 450 patients with metastatic non‐small cell lung cancer (NSCLC) treated with second‐line nivolumab at 17 centers between 2016 and 2024. Among these patients, 118 (26.2%) had DM.
Emre Çakır, Didem Divriklioğlu, Deniz Can Güven, Gamze Serin Özel, Oğuzhan Yıldız, Gamze Emin, Merve Keskinkılıç, Yeşim Ağyol, Onur Yazdan Balçık, Nagihan Kolkıran, Hale Gülçin Yıldırım Doğan, Pervin Can Şancı, Özge Yalıcı, Teoman Şakalar, Yurdagül Danacı, Yakup Düzköprü, Canan Yıldız, Mesut Yılmaz, İlhan Hacıbekiroğlu, Bülent Erdoğan, Saadettin Kılıçkap, Gamze Gököz Doğu, Melek Karakurt Eryılmaz, Atila Yıldırım, İlhan Öztop, İbrahim Vedat Bayoğlu, Şahnura Uzuntaş, Atike Pınar Erdoğan, Emir Çelik, Devrim Çabuk, Erdoğan Selçuk Şeber, Zehra Sadak Öcal, Hacer Demir   +32 more
wiley   +1 more source

Urethral injury during vaginal delivery: Incidence, management and long‐term outcomes

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study examines the incidence, obstetric risk factors, surgical management, and long‐term outcomes of obstetric‐associated urethral injuries during vaginal deliveries. Methods A retrospective case series was conducted at a single, tertiary university‐affiliated medical center between January 2018 and December 2023.
Yoav Baruch, Ronen Gold, Yariv Stabholz, Michael Lavie, Yariv Yogev, Asnat Groutz   +5 more
wiley   +1 more source

Mesenteric Adipose Tissue as a Modulator of Intestinal Inflammation: Mechanistic Insights and Model Systems in Crohn's Disease. [PDF]

Eur J Immunol
Omar T, Weidinger C, Siegmund B.
europepmc   +1 more source

α2,3‐Sialyltransferase (ST3Gal1) regulates endometrioid‐type epithelial ovarian cancer cell migration and invasion via VEGF‐R2/JAK2/STAT3 signaling cascades

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To investigate the role of ST3 β‐galactoside α‐2,3‐sialyltransferase 1 (ST3Gal1) and vascular endothelial growth factor receptor 2 (VEGF‐R2) in endometrioid‐type epithelial ovarian cancer (E‐OC) because aberrant α2,3‐sialylation mediated by ST3Gal1 and VEGF‐R2‐related angiogenesis is linked with tumor progression. Methods ST3Gal1 and
Wei‐Ting Chao, Chia‐Hao Liu, Szu‐Ting Yang, Chen‐Hao Lin, Liang‐Wei Wang, Peng‐Hui Wang   +5 more
wiley   +1 more source

Irritable Bowel Syndrome Prevalence in Patients with Inflammatory Bowel Disease in Remission: Single-Center Experience. [PDF]

Clin Exp Gastroenterol
Golubovic O, Knezevic Ivanovski T, Kralj D, Mitrovic M, Milić A, Svorcan P, Markovic S.   +6 more
europepmc   +1 more source

Engineering Bacteria for Medicine: Delivery, Diagnosis, and Therapy

iMetaMed, EarlyView.
ABSTRACT With rapid advances in synthetic biology and genetic engineering, genetically engineered bacteria (GEB) have emerged as a promising platform for biological therapy, addressing key limitations of conventional drug delivery systems and demonstrating significant clinical potential.
Shiyu Xia, Guiling Fu, Xiaoyue Ding, Wen Yang, Ruijie Bai, Yawei Cai, Jing xuan Zhang, Yanxia Wei, Conghui Han, Yi‐Zhou Gao, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

MAIT Cells Maintain Intestinal Homeostasis Through IL-22 in an Experimental Colitis. [PDF]

J Inflamm Res
Peng Y, Zheng C, Wang Y, Huang F, Shao Y, Liu L, Zhao Q.   +6 more
europepmc   +1 more source

Bile acid metabolism and signaling in human and animal health: A One Health perspective

iMetaOmics, EarlyView.
Bile acids maintain host homeostasis through enterohepatic circulation, microbial transformation, and bile acid receptor signaling, thereby regulating glucose and lipid metabolism, intestinal barrier integrity, and immunity. These effects support human disease intervention and health‐oriented animal production, reducing drug dependence and residue ...
Lei Li, Shuai Liu, Zhijun Cao, Yangchun Cao, Shengru Wu, Lu Deng, Junhu Yao, Jun Zhang   +7 more
wiley   +1 more source