Results 221 to 230 of about 293,895 (310)

Modulating Lysine Crotonylation in Ulcerative Colitis Maintains Mitochondrial Homeostasis

Exploration, EarlyView.
NaCr promotes KCr to impede the inflammatory progression of ulcerative colitis. KCr induces mitophagy by activating the PINK1/PARKIN pathway to restrict NLRP3 inflammasome activation, thereby decreasing the production and release of various inflammatory cytokines, such as IL‐1β and TNF‐α. KCr induces mitophagy and inhibits NLRP3 inflammasome activation
Tongtong Liu, Binyan Lin, Ying Zhang, Jiayu Su, Xiaochao Hu, Xuan Wang, E‐Hu Liu, Shijia Liu   +7 more
wiley   +1 more source

Correction to: Fecal Microbial Community Profiling Allows Discrimination of Phenotype and Treatment Response in Pediatric Crohn's Disease and Ulcerative Colitis-An International Meta-Analysis. [PDF]

Inflamm Bowel Dis
europepmc   +1 more source

Ulcerative colitis and colorectal cancer: Pathogenic insights and precision strategies for prevention and treatment. [PDF]

World J Gastrointest Oncol
Catalano M, Mini E, Nobili S, Vascotto IA, Ravizza D, Amorosi A, Tonelli F, Roviello F, Roviello G, Nesi G.   +9 more
europepmc   +1 more source

Gut‐Targeted Nutraceutical Delivery: Engineering Microbiome‐Responsive Nutraceutical Interfaces

Food Bioengineering, EarlyView.
ABSTRACT The gut microbiome plays a central role in maintaining host health, influencing immunity, metabolism, epithelial integrity, and the gut–brain axis. Dysbiosis of this complex microbial ecosystem is implicated in a variety of chronic diseases, including inflammatory bowel disease, metabolic syndrome, and neurological disorders.
Jeyavelkumaran Renukadevi, Muthu Ranjani, Panneerselvam Sneha, Jahir Safiq Hussain, Harikrishnan Shakthi   +4 more
wiley   +1 more source

Safflower Polysaccharides Alleviate TNBS-Induced Colitis by Modulating Gut Immunity. [PDF]

Foods
Jiang C, Zhu F, Aimaier S, Zhang L, Ali MH, Fan F, Lu Y, Jia M, Wu D, Yin H, Wei J, Chu S, Liu M.   +12 more
europepmc   +1 more source

Role of the Choline‐Binding Protein A in the Ability of Porcine Ligilactobacillus salivarius FFIG58 to Modulate TLR3‐Mediated Intestinal Antiviral Immunity

Food Frontiers, EarlyView.
The choline‐binding protein A (CbpA) was shown to mediate adhesion of probiotic Ligilactobacillus salivarius strains to human intestinal epithelial cells (IECs). A knockout mutant lacking the CbpA protein derived from the immunomodulatory porcine strain L. salivarius FFIG58 was obtained. The CbpA is a key surface protein of L.
Yoshiya Imamura, Hikari Yamamuro, Mariano Elean, Lorena Paola Arce, Ryutaro Funabashi, Fernanda Raya Tonetti, Kohtaro Fukuyama, Mikado Tomokiyo, Fu Namai, Sudeb Saha, Wakako Ikeda‐Ohtsubo, Keita Nishiyama, Julio Villena, Haruki Kitazawa   +13 more
wiley   +1 more source

Pramipexole Exerts Beneficial Effects in a Rat Model of Acetic Acid-Induced Colitis via Modulating Inflammation. [PDF]

Adv Biomed Res
Motavallian A, Ghazizadeh F, Khoshbin SP, Karimian P, Aghajani Torshkooh F.   +4 more
europepmc   +1 more source

Natural Melanin From Silky Fowl (Gallus gallus domesticus Brisson): Characterization and Protection of Caco‐2 Cells From Oxidative Stress via the Akt/Nrf2 Pathway

Food Frontiers, EarlyView.
(created with BioRender.com) ABSTRACT Silky fowl, a unique chicken breed, exhibits black skin, meat, and bones due to the presence of natural melanin pigments. In our study, melanin from silky fowl (MSF) was isolated using an enzymatic extraction procedure and identified as a unique natural antioxidant.
Chunhui Xu, Shibao Li, Xuan Huang, Yunyan Huang, Yuting Tan, Zhaozheng Yin   +5 more
wiley   +1 more source

Kaempferol Alleviates Acrolein‐Induced Lung Injury In Vitro and In Vivo by Binding to Peli2 and Disrupting the Peli2‐NLRP3 Interaction

Food Frontiers, EarlyView.
Abstract Acrolein (ACR) is a highly toxic agent that induces lung inflammation and causes acute lung injury (ALI). However, effective treatments for ACR‐induced ALI are currently lacking. We investigated the protective effects of kaempferol (Kae) against ACR‐induced ALI using in vitro (HBE and BEAS‐2B cells) and in vivo murine models (male C57BL/6 mice)
Juanjuan Ma, Zhao Yin, Jie Zheng, Xingyou Mo, Shaoji Li, Hua Liu, Shiyi Ou   +6 more
wiley   +1 more source

Microscopic colitis in alopecia areata: A gut-skin connection beyond the follicle. [PDF]

JAAD Int
Hirpara M, Greene R, Chapman M, Albers CG, Mesinkovska N.   +4 more
europepmc   +1 more source