Machine learning identifies a distinct microbiota signature in immune checkpoint inhibitor colitis compared with inflammatory bowel disease. [PDF]
Barberio B +17 more
europepmc +1 more source
Association Between Microscopic Colitis and Parkinson's Disease in a Swedish Population
Xiaoying Kang +7 more
openalex +1 more source
Isoform Specificity of a Compound Targeting Actin Filaments Containing Tropomyosin Tpm1.8/1.9
ABSTRACT The unbranched actin filaments in mammalian cells are usually composed of co‐polymers of a specific tropomyosin isoform with actin. Genetic manipulation has revealed that the tropomyosins largely define the functional properties of actin filaments in an isoform‐specific, non‐redundant manner.
Jeff Hook +2 more
wiley +1 more source
Parasitic colitis misdiagnosis as inflammatory bowel disease in high-income settings and association with poor clinical outcomes when exposed to corticosteroids: a systematic review of case reports. [PDF]
Lees RD +6 more
europepmc +1 more source
Butyrate and mucosal inflammation: New scientific evidence supports clinical observation [PDF]
Alvarado, David M. +2 more
core +3 more sources
Model‐Informed Deep Q‐Networks to Guide Infliximab Dosing in Pediatric Crohn’s Disease
Model‐informed precision dosing (MIPD) utilizes pharmacokinetic/pharmacodynamic (PK/PD) models to optimize drug therapy. However, conventional MIPD often requires manual simulation and regimen selection, which are time‐consuming and demand specialized expertise.
Kei Irie +6 more
wiley +1 more source
Bidirectional microbial regulation by tyrosine metabolism enhances palmatine-mediated colitis protection. [PDF]
Sun D +8 more
europepmc +1 more source
Vedolizumab as induction and maintenance therapy for ulcerative colitis.
B. Feagan +15 more
semanticscholar +1 more source
High‐dose methotrexate for pediatric cancer treatment is frequently associated with mucositis, which can lead to delayed or discontinued treatment and impact survival. While individual genetic variants have been implicated, the cumulative impact of genetic variation within relevant biological pathways remains unexplored.
Xiao Yu Cindy Zhang +9 more
wiley +1 more source

