Results 71 to 80 of about 940,030 (267)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Mid-level managers’ perspectives on implementing isoniazid preventive therapy for people living with HIV in Ugandan health districts: a qualitative study

BMC Health Services Research
Background Isoniazid preventive therapy (IPT) works to prevent tuberculosis (TB) among people living with HIV (PLHIV), but uptake remains low in Sub-Saharan Africa.
Canice Christian, Elijah Kakande, Violah Nahurira, Cecilia Akatukwasa, Fredrick Atwine, Robert Bakanoma, Harriet Itiakorit, Asiphas Owaraganise, William DiIeso, Derek Rast, Jane Kabami, Jason Johnson Peretz, Starley B. Shade, Moses R. Kamya, Diane V. Havlir, Gabriel Chamie, Carol S. Camlin   +16 more
doaj   +1 more source

Variations of high frequency parameter of heart rate variability following osteopathic manipulative treatment in healthy subjects compared to control group and sham therapy: randomized controlled trial

Frontiers in Neuroscience, 2015
Context: Heart Rate Variability (HRV) indicates how heart rate changes in response to inner and external stimuli. HRV is linked to health status and it is an indirect marker of the autonomic nervous system (ANS) function.
Nuria eRuffini, Giandomenico eD'alessandro, Nicolò eMariani, Alberto ePollastrelli, Lucia eCardinali, Francesco eCerritelli   +5 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Changes in susceptibility of Plasmodium falciparum to antimalarial drugs in Uganda over time: 2019–2024

Nature Communications
The treatment and control of malaria in Africa is challenged by drug resistance. We characterized ex vivo susceptibilities to nine drugs of isolates collected from individuals presenting with uncomplicated falciparum malaria in eastern (2019-2024) and ...
Martin Okitwi, Stephen Orena, Patrick K. Tumwebaze, Thomas Katairo, Yoweri Taremwa, Oswald Byaruhanga, Stephen Tukwasibwe, Samuel L. Nsobya, Jennifer Legac, Jeffrey A. Bailey, Roland A. Cooper, Melissa D. Conrad, Philip J. Rosenthal   +12 more
doaj   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

FEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai, Yong Xu, Jingjing Ma, Ratchanee Duangrat, Chen Yan, Jingyan Liang, Hua Wei, Bin Jiang, Tao‐Sheng Li   +8 more
wiley   +1 more source

Dynamic Epidural Monitoring of Spinal Cord Neural Conduction Using a Novel Implantable Electrodiagnostic Sensor: A Pre Clinical Study

Neurotrauma Reports
To evaluate the feasibility and diagnostic sensitivity of a novel catheter-based epidural electrodiagnostic (EDX) system for real-time, segment-specific monitoring of spinal somatosensory conduction in a pre-clinical model of acute spinal cord injury ...
Babak Shadgan, Alexander Burden, Jocelyn Bégin, Min Lu, Shahbaz Askari   +4 more
doaj   +1 more source

Hypertension control in integrated HIV and chronic disease clinics in Uganda in the SEARCH study

BMC Public Health, 2019
Background There is an increasing burden of hypertension (HTN) across sub-Saharan Africa where HIV prevalence is the highest in the world, but current care models are inadequate to address the dual epidemics.
Dalsone Kwarisiima, Mucunguzi Atukunda, Asiphas Owaraganise, Gabriel Chamie, Tamara Clark, Jane Kabami, Vivek Jain, Dathan Byonanebye, Florence Mwangwa, Laura B. Balzer, Edwin Charlebois, Moses R. Kamya, Maya Petersen, Diane V. Havlir, Lillian B. Brown   +14 more
doaj   +1 more source

Collaboration [PDF]

Analytical Chemistry, 2021
openaire   +2 more sources

Collaborative Performance

International Journal of e-Collaboration, 2010
Collaboration is gaining attention as a key driver of overall business performance, innovation capabilities and productivity. However, there is a discrepancy between the perceived importance of collaboration and the extent to which companies approach collaboration in a structured manner.
Kristensen, Kjetil, Kijl, Björn
openaire   +3 more sources