Results 81 to 90 of about 1,314,644 (308)

Student staff partnership to create an interdisciplinary science skills course in a research intensive university [PDF]

, 2015
This paper reflects upon the development of a multidisciplinary lesson plan aimed at developing science skills for Physics and Astronomy, Geographical and Earth Sciences, and Chemistry students at a research intensive Scottish university. The lesson plan
Curry, Gordon, Fehertavi, Szonja, Hill, Bob, Longbone, Charlotte, Sneddon, Peter, Wallace, Katherine, Woolmer, Cherie   +6 more
core   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Analysis of Collaboration Ability in the RADEC Learning Model for Elementary School Students

Mimbar Sekolah Dasar
This study investigates the effectiveness of the Read, Answer, Discuss, Explain, and Create (RADEC) learning model in fostering collaboration skills among elementary school students during electricity science lessons.
Mohamad Yasin As'ary, Atep Sujana, Wahyu Sopandi   +2 more
doaj   +1 more source

Cross-disciplinary Collaboration and Health Promotion in Schools [PDF]

, 2012
School-based social workers, collaborating with teachers, can contribute to the development of the skills, knowledge, and attitudes required for individuals to live healthy lives both in the short and long term.
Testa, Doris
core   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Exploration and practice of the “SPOC+PAD class” blended teaching model in the course of epidemiology

Frontiers in Education
BackgroundThe blended teaching model of “online theory + offline practice” has become a focal point in the new era of medical education. However, the combination of Small Private Online Course and Presentation-Assimilation-Discussion (SPOC+PAD) classroom
Haomin Yang, Haomin Yang, Rong Fu, Tao Lin, Fei He   +4 more
doaj   +1 more source

Necessary skills and practices required for effective participation in high bandwidth design team activities [PDF]

, 2004
Technology is continually changing, and evolving, throughout the entire construction industry; and particularly in the design process. One of the principal manifestations of this is a move away from team working in a shared work space to team working ...
Bellamy, Tom, Gameson, Rod, Sher, Willy, Williams, Anthony   +3 more
core   +1 more source

The Data Management Skills Support Initiative: synthesising postgraduate training in research data management [PDF]

, 2012
<p>This paper will describe the efforts and findings of the JISC Data Management Skills Support Initiative (‘DaMSSI’). DaMSSI was co-funded by the JISC Managing Research Data programme and the Research Information Network (RIN), in partnership with
Molloy, L., Snow, K.
core   +3 more sources

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source