Results 91 to 100 of about 6,929,436 (348)

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Delivering perinatal depression care in a rural obstetric setting: a mixed methods study of feasibility, acceptability and effectiveness

Journal of Psychosomatic Obstetrics and Gynecology, 2018
Objectives: Universal screening for depression during pregnancy and postpartum is recommended, yet mental health treatment and follow-up rates among screen-positive women in rural settings are low.
Amritha Bhat, Susan Reed, Johnny Mao, Mindy Vredevoogd, Joan Russo, Jennifer Unger, Roger Rowles, Jürgen Unützer   +7 more
doaj   +1 more source

Long-term clinical and cost-effectiveness of collaborative care (versus usual care) for people with mental–physical multimorbidity: cluster-randomised trial

The British journal of psychiatry : the journal of mental science, 2018
Background Collaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown.
E. Camacho, L. Davies, M. Hann, Nicola Small, P. Bower, C. Chew‐Graham, Clare Baguely, L. Gask, C. Dickens, K. Lovell, W. Waheed, C. Gibbons, P. Coventry   +12 more
semanticscholar   +1 more source

Mind Mapping: A Strategy to Promote Interprofessional Collaboration among Health Science Students [PDF]

, 2016
Purpose/Background: This presentation will provide participants with an understanding of what mind mapping is and engage participants in a discussion and hands on experience of how mind mapping can be used to prepare students for interprofessional ...
Maher, PT, DPT, Catherine, Pinto Zippo, PT, EdD, Genevieve   +1 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

Compassionate collaborative care: an integrative review of quality indicators in end-of-life care

BMC Palliative Care, 2017
BackgroundCompassion and collaborative practice are individually associated with high quality healthcare. When combined in a compassionate collaborative care (CCC) practice framework, they are reported to improve health, strengthen care provision, and ...
Kathryn A. Pfaff, Adelais Markaki
semanticscholar   +1 more source

CARE-PACT: a new paradigm of care for acutely unwell residents 
in aged care facilities [PDF]

, 2015
Describes the Comprehensive Aged Residents Emergency and Partners in Assessment, Care and Treatment (CARE-PACT) program: a hospital substitutive care and demand management project that aims to improve, in a fiscally efficient manner, the quality of care ...
Ellen Burkett, Ian Scott
core  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Effects of changing veterinary handling techniques on canine behaviour and physiology Part 2: Behavioural measurements

Animal Welfare
Signs of distress in dogs during veterinary visits are often normalised rather than viewed as welfare concerns. Interventions designed to reduce fear during veterinary visits were evaluated to see if they affected dogs’ behaviours compared to dogs ...
Camille Squair, Kathryn Proudfoot, William Montelpare, Tracy Doucette, Karen L Overall   +4 more
doaj   +1 more source