Results 91 to 100 of about 451,231 (312)
Collaborative support for distributed design [PDF]
A number of large integrated projects have been funded by the European Commission within both FP5 and FP6 that have aimed to develop distributed design solutions within the shipbuilding industry. VRShips-ROPAX was funded within FP5 and aimed to develop a
Whitfield, R.I., Duffy, A.H.B.
core
Observing network characteristics in mass collaboration design projects
Mass collaboration efforts can increase innovation and design possibilities. Incorporation of open innovation into the product development process allows for a vast array of unique perspectives and ideas.
Zachary Ball, Kemper Lewis
doaj +1 more source
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Information and IN-formation -Information mining for supporting collaborative design [PDF]
Collaborative design has become a research paradigm in design studies. To make effective collaborative design, an information service mechanism for helping collaborators to access related information of specific design situation is getting important ...
M.L. Chiu, J.H. Lan
core
Support for collaborative design reasoning in shared virtual spaces [PDF]
This paper discusses collaborative design, emphasizing the elaboration and transformations of a problem space, and the role that unstructured verbal communication and graphic communication can play in these processes. An asynchronous collaborative system,
Craig Zimring +3 more
core +1 more source
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Using design performance measurement as a strategy to improve collaborative design performance [PDF]
This research investigates how to improve collaborative design performance by the implementation of performance measurement. A Design Performance Measurement (DPM) framework is developed to measure collaborative design performance and identify strengths ...
Qin, Sheng-feng +3 more
core
A framework for collaborative working environments [PDF]
To utilize the advantages of existing and emerging Internet techniques and to meet the demands for a new generation of collaborative working environments, a framework with an upperware-middleware architecture is proposed, which consists of four layers ...
Ji, Shuyan +7 more
core +1 more source
Strategic risk dominance in collective systems design
Engineered system architectures leveraging collaboration among multiple actors across organizational boundaries are envisioned to be more flexible, robust, or efficient than independent alternatives but also carry significant downside risks from new ...
Paul T. Grogan, Ambrosio Valencia-Romero
doaj +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

