Results 91 to 100 of about 63,328,130 (338)

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Collaborative Categorization on the Web [PDF]

open access: yes, 2003
Collaborative categorization is an emerging direction for research and innovative applications. Arguably, collaborative categorization on the Web is an especially promising emerging form of collaborative Web systems because of both, the widespread use
Bry, François, Wagner, Holger
core   +1 more source

Strategy and Impact of Liner Shipping Schedule Recovery under ECA Regulation and Disruptive Events

open access: yesJournal of Marine Science and Engineering
In the post-pandemic era, the complexity of the international shipping situation, such as environmental policies, port congestion, and local conflicts, poses challenges to the stability of liner shipping, which requires strict adherence to schedules ...
Jingmiao Zhou   +3 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Valuation Studies: A Collaborative Valuation in Practice

open access: yesValuation Studies, 2014
This discussion note provides a perspective on valuation studies by a group of PhD students. Based on impressions from the Valuation as Practice workshop at The University of Edinburgh in early 2014 we were inspired by the example of Kjellberg et al ...
Gordon Haywood   +7 more
doaj   +1 more source

Introducing Collaborative Practices to Undergraduate Studies [PDF]

open access: yes, 2016
The changes in software industry and software development methods call for appropriate teaching methods in academia. In addition to theoretical knowledge and coding practice, familiarity with common practices in the industry is expected from the graduates.
Jaana Holvikivi   +2 more
openaire   +3 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Designers' experience and collaborative design : two case studies [PDF]

open access: yes, 2009
Experience underlies all kinds of human knowledge and determines how people interact with products and environments. It also influences designers’ knowledge and their design process.
Popovic, Vesna   +2 more
core   +2 more sources

Latin American Collaborative Study of Congenital Malformations (ECLAMC): A Model for Health Collaborative Studies

open access: yesPublic Health Genomics, 2014
Fil: Castilla, Eduardo Enrique. Consejo Nacional de Investigaciones Científicas y Técnicas. Oficina de Coordinación Administrativa Parque Centenario. CEMIC-CONICET. Centro de Educaciones Médicas e Investigaciones Clínicas ; Argentina.
Poletta, Fernando Adrián   +2 more
openaire   +3 more sources

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