Results 101 to 110 of about 63,328,130 (338)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

FEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

Collaborative Environments. Considerations Concerning Some Collaborative Systems [PDF]

It is obvious, that all collaborative environments (workgroups, communities of practice, collaborative enterprises) are based on knowledge and between collaboration and knowledge management there is a strong interdependence.
Mihaela I. MUNTEAN
core  

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Decarbonising Transport – The Spatial Effects of Railway Container Transport on Carbon Emissions

Promet (Zagreb)
China is advancing a strategic transport shift to establish railway container transport as a key logistics pillar, supporting its dual carbon goals through sector restructuring.
Zhizhen BAI, Xiaodong LI, Haibo KUANG
doaj   +1 more source

Collaborative studies of U.S.-China neurologists on acute motor axonal neuropathy. [PDF]

Pediatr Investig, 2022
Lv J, Zhaori G.
europepmc   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Perspective (Institute for Christian Studies)

, 2015
The laudatio for Dianne Bergsma by James Olthuis appeared in Perspective 48, no. 2 (Sept 2014) http://hdl.handle.net/10756/332755Master of Worldview Studies: To New York and Beyond -- Student Achievements -- Enhancing Global Access to ICS Research ...
Guthrie-McNaughton, Isabella, Hoff, Shannon, Ansell, Nicholas, Institute for Christian Studies, Blomberg, Doug, Sweetman, Robert, Kuipers, Ronald A., Strauss, Gideon, Witvoet, Bert   +8 more
core   +1 more source

Challenges hindering emergency physicians; involvement in multicenter collaborative studies in Japan: A nationwide survey analysis. [PDF]

Acute Med Surg, 2023
Yasuda M, Saito A, Goto T, Yamamoto R, Liu K, Kuriyama A, Kondo Y, Kasugai D, RED‐PAM study investigators.   +8 more
europepmc   +1 more source