Results 81 to 90 of about 1,882,538 (310)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Valuation Studies: A Collaborative Valuation in Practice

Valuation Studies, 2014
This discussion note provides a perspective on valuation studies by a group of PhD students. Based on impressions from the Valuation as Practice workshop at The University of Edinburgh in early 2014 we were inspired by the example of Kjellberg et al ...
Gordon Haywood, Johan Nilsson, Michael Franklin, Paul Gilbert, Linus Johansson Krafve, Lisa Lindén, Mark MacGillivray, Robert Meckin   +7 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Strategy and Impact of Liner Shipping Schedule Recovery under ECA Regulation and Disruptive Events

Journal of Marine Science and Engineering
In the post-pandemic era, the complexity of the international shipping situation, such as environmental policies, port congestion, and local conflicts, poses challenges to the stability of liner shipping, which requires strict adherence to schedules ...
Jingmiao Zhou, Yuzhe Zhao, Xinran Yan, Meican Wang   +3 more
doaj   +1 more source

Collaborative improvement as an inspiration for supply chain collaboration [PDF]

, 2002
The battlefield of competition is today moving from the level of\ud individual firms to the one of the extended enterprises, that is, networks of customers and their suppliers. This paper discusses how learning and continuous improvement today take place
Cagliano, Raffaella, Caniato, Federico, Corso, Mariano, Gieskes, José, Middel, Rick, Spina, Gianluca   +5 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Harmonization of Collaborative Study Protocols

Journal of AOAC INTERNATIONAL, 1986
Abstract The 2 major protocols for the design, conduct, and interpretation of collaborative analytical studies—those from AOAC and the International Organization for Standardization—are already fairly well harmonized. The statistical models are identical and the outlier tests are essentially the same. The major differences are in symbols
openaire   +2 more sources

Using Evaluation to Foster NYCETP Goals: Case Studies and Intercampsus Collaboration [PDF]

, 2000
This article describes the use of case studies as part of the formative evaluation conducted for the New York Collaborative for Excellence in Teacher Preparation (NYCETP).
Flugman, B., Pape, S. J., Tittle, C K.
core   +1 more source

Facilitating collaborative knowledge construction in computer-mediated learning with structuring tools [PDF]

, 2003
Collaborative knowledge construction in computer-mediated learning environments puts forward difficulties regarding what tasks learners work on and how learners interact with each other.
Ertl, Bernhard, Fischer, Frank, Mandl, Heinz, Reiserer, Markus, Weinberger, Armin   +4 more
core   +2 more sources

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source