Results 81 to 90 of about 1,983,281 (299)

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

FEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman, Jessica Haines, Connie Pritchard, Stephen Rutherford, Nigel Francis   +4 more
wiley   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Integrating Behavioral Health & Primary Care in New Hampshire: A Path Forward to Sustainable Practice & Payment Transformation [PDF]

, 2016
New Hampshire residents face challenges with behavioral and physical health conditions and the interplay between them. National studies show the costs and the burden of illness from behavioral health conditions and co-occurring chronic health conditions ...
Bartels, Stephen J., Beaty, Sharon, Blount, Alexander, Brewster, William, Bujno, Lisa, Cameron, Stephanie, Coursin, David, Doyle, Marcy, Garin, Hwasun, Goldsberry, Yvonne, Gunn, William, Highland, James, Hodder, Lucy C., Lotz, Doris, Miller, Patrick, Montero, Jose, Nichols, Susan, O’Neil, Molly, Pepin, Amy, Porter, Josephine, Ryer, Jeanne, EdD, Thomas, Janet, Tutko, Holly Deblois   +22 more
core   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Permanent training for teachers of “Parque Explora” An approach to the learning community Astromae

Senderos Pedagogicos, 2017
The article it is a cuantitative investigation called permanent formation for teachers in different places of the facultates of education a study of case in relation with the Teachers Friends of Explora-Astromae.
Luisa Fernanda Casas Fernández, Juan Pablo Suárez Vallejo   +1 more
doaj   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Dialogical identities in students from cultural minorities or students categorised as presenting SEN: How do they shape learning, namely in mathematics? [PDF]

, 2007
Portuguese schools are multicultural. Diversity is their main characteristic. Portuguese policy documents assume inclusive principles (Ainscow & César, 2006).
César, Margarida
core  

Enhancing Oncological Care for India's Aging Population: Addressing the Complex Needs of Older Adults With Cancer

Aging and Cancer, EarlyView.
Aging‐associated physiological and molecular alterations pose significant challenges in cancer management among India's elderly. Limited geriatric oncology expertise, financial constraints, and inadequate specialized care exacerbate disparities. Strategic expansion of insurance coverage, integration of palliative care, and infrastructural advancements ...
Nihanthy D. Sreenath, Mathigatta Shivarudraiah S, Rajath Govind, Kaushik M R   +3 more
wiley   +1 more source

Document-related Awareness Elements in Synchronous Collaborative Authoring [PDF]

, 2006
Simultaneous collaboration on documents by distributed authors has been supported by numerous synchronous collaborative authoring systems that are widely available.
Raikundalia, Gitesh K, Zhang, Hao Lan
core  

Sustainable landscape management based on cultural ecosystem services

Change and Adaptation in Socio-Ecological Systems, 2017
To sustain cultural ecosystem services and cultural heritage it is important to go in depth in the science policy interface, because efficient governance mechanisms emerge from the cooperation of scientists and practitioners.
Palacios-Agundez Igone, Peña Lorena, Ametzaga-Arregi Ibone, Rodríguez-Loinaz Gloria, Onaindia Miren   +4 more
doaj   +1 more source