Results 81 to 90 of about 14,097,489 (290)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Hydrostatic pressure activates HIF‐1α via β‐catenin to promote stemness in breast cancer cells

open access: yesFEBS Open Bio, EarlyView.
To mimic the elevated intestinal fluid pressure in breast cancers, we loaded human breast cancer cells (MCF‐7, MDA‐MB‐453, and BT‐474) to 50 mmHg hydrostatic pressure. Hydrostatic pressure exposure upregulated HIF‐1α and induced stemness in MCF‐7 and BT‐474 cells.
Da Zhai   +8 more
wiley   +1 more source

Uncovering Myself to Understand You

open access: yesColombian Applied Linguistics Journal, 2017
Classroom incidents in which teachers have to exhibit their expertise at managing a class is a commonplace in teachers´ daily routines; though sometimes some of those classroom incidents turn into critical moments.
Sayra Milena Lozano Carvajal   +1 more
doaj   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

Paper vs. tablets : The effect of document media in co-located collaborative work [PDF]

open access: yes, 2014
Funding: TR Tech, Surfnet, GRAND, AITF, CFI, NSERC and Smart Technologies.With new computer technologies portable devices are rapidly approaching the dimensions and characteristics of traditional pen and paper-based tools.
Miguel A. Nacenta   +5 more
core   +1 more source

Collaborative Work with Highly Automated Marine Navigation Systems. [PDF]

open access: yesComput Support Coop Work, 2022
Veitch E   +3 more
europepmc   +1 more source

Data and Task Offloading in Collaborative Mobile Fog-Based Networks

open access: yesIEEE Access, 2019
The rapid growth of mobile devices in recent years has led to the rapid progress of mobile computing. However, this has exposed certain limitations that have, first, been addressed by mobile cloud computing.
Radu-Ioan Ciobanu   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

open access: yesFEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito   +7 more
wiley   +1 more source

Culture, role and group work : a social network analysis perspective on an online collaborative course [PDF]

open access: yes, 2013
This paper discusses the patterns of network dynamics within a multicultural online collaborative learning environment. It analyses the interaction of participants (both students and facilitators) within a discussion board that was established as part of
Roger Dalrymple   +8 more
core   +1 more source

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