Results 131 to 140 of about 1,205,834 (339)

Expanding Chemical Space of Nucleic Acid Nanoparticles for Tunable Antiviral‐Like Immunomodulatory Responses and Potent Adjuvant Activity

Advanced Functional Materials, EarlyView.
We introduce a nucleic acid nanoparticle (NANP) platform designed to be rrecognized by the human innate immune system in a regulated manner. By changing chemical composition while maintaining constant architectural parameters, we identify key determinants of immunorecognition enabling the rational design of NANPs with tunable immune activation profiles
Martin Panigaj, Hannah S. Newton, Jian Wang, Laxmi Pandey, Yelixza I. Avilla, Phong Nguyen, Morgan Chandler, Justin Halman, Yasmine Radwan, Stephanie Smith, Elijah Edmondson, Simone Difilippantonio, Chelsea Sanders, Bao Tran, Yongmei Zhao, Shaojun Xie, Edward Cedrone, Barry W. Neun, Meni Wanunu, Nikolay V. Dokholyan, Marina A. Dobrovolskaia, Kirill A. Afonin   +21 more
wiley   +1 more source

Modulation of hide protein resistance to enzymatic hydrolysis by calcium ions: rational design of enzyme-assisted unhairing for high-quality leather production

Collagen and Leather
Enzymatic unhairing is an environmentally friendly and efficient method for leather processing. However, controlling protease hydrolysis remains challenging, leading to incomplete hair removal and potential grain damage.
Hao Liu, Xuyang Chen, Juntao Kang, Bi Shi, Yunhang Zeng   +4 more
doaj   +1 more source

A Vascular Microphysiological Model of Lung Fibrosis Reveals That Myofibroblasts and IPF Patient‐Derived Fibroblasts Impair Angiogenesis and Vasculogenesis

Advanced Functional Materials, EarlyView.
A microphysiological lung fibrosis model recapitulates myofibroblast–vascular interactions. Induced myofibroblasts and patient‐derived IPF fibroblasts impair angiogenesis and increase vascular permeability via TGF‐β1–driven signaling. Pharmacological interventions with SB 431542 and VEGF supplementation restore vascular morphology and barrier function.
Elena Cambria, Adriana Blazeski, Eunkyung Clare Ko, Tran Thai, Shania Dantes, David A. Barbie, Sarah E. Shelton, Roger D. Kamm   +7 more
wiley   +1 more source

Nitrogen-rich fibrous carbon enabling polysulfide conversion for lithium–sulfur batteries

Collagen and Leather
The practical implementation of lithium–sulfur (Li–S) batteries is hindered by their poor rate performance and rapid capacity fade, primarily due to the sluggish kinetics of polysulfide conversion.
Hai Lin, Zhen Du, Lingyong Xu, Chengming Li, Yuepeng Guan, Yaqin Huang   +5 more
doaj   +1 more source

Collagen‐Bound α₁‐Microglobulin in Normal and Healed Tissues and its Effect on Immunocompetent Cells [PDF]

, 1999
Santin, Cannas
openalex   +1 more source

Collagens [PDF]

Journal of Clinical Pathology, 1978
openaire   +3 more sources

Ca2+ - Induced Structural Change of Multi-Domain Collagen Binding Segments of Collagenases ColG and ColH from Hathewaya histolytica [PDF]

, 2018
Hathewaya histolytica, previously renamed as Clostridium histolyticum, secretes at least two collagenases, ColH and ColG, that allow for degradation of extracellular matrices of animal tissue.
Ruth, Christopher Eric
core   +2 more sources

A Smart Bio‐Battery Facilitates Diabetic Bone Defect Repair Via Inducing Macrophage Reprogramming and Synergistically Modulating Bone Remodeling Coupling

Advanced Functional Materials, EarlyView.
This research presents a novel implantable bio‐battery, GF‐OsG, tailored for diabetic bone repair. GF‐OsG generates microcurrents in high‐glucose conditions to enhance vascularization, shift macrophages to the M2 phenotype, and regulate immune responses.
Nanning Lv, Haifu Sun, Wenxiang Tang, Yonggang Li, Zhonglai Qian, Lihui Hong, Chong Chen, Hongye Li, Jiaxiang Bai, Yusen Qiao, Mingming Liu   +10 more
wiley   +1 more source

Multifunctional hydrogel–acellular dermal matrix composite patch: an anticalcification barrier with antibacterial and anti-inflammatory properties for abdominal wall repair

Collagen and Leather
Calcification, infection, and inflammation are common complications associated with the in vivo application of biological patches. Porcine acellular dermal matrix (pADM), composed mainly of collagen with excellent bioactivity, is widely utilized as a ...
Xin Zheng, Ying Zhang, Nianhua Dan, Yining Chen, Zhengjun Li, Yunbing Wang   +5 more
doaj   +1 more source

Region‐to‐Region Unidirectional Connection In Vitro Brain Model for Studying Directional Propagation of Neuropathologies

Advanced Functional Materials, EarlyView.
A unidirectional cerebral organoid–organoid neural circuit is established using a microfluidic platform, enabling controlled directional propagation of electrical signals, neuroinflammatory cues, and neurodegenerative disease–related proteins between spatially separated organoids.
Kyeong Seob Hwang, Hui‐Wen Liu, Hyogeun Shin, Hyun Wook Kang, Minjin Kang, Jongbaeg Kim, Il‐Joo Cho, Nakwon Choi, Seok Chung, Hong Nam Kim   +9 more
wiley   +1 more source