Results 1 to 10 of about 475,600 (180)

Complications of corneal collagen cross-linking [PDF]

Indian Journal of Ophthalmology, 2022
Corneal collagen cross-linking (CXL) is an effective treatment for arresting progression in patients with keratoconus. CXL was approved by United States Food and Drug Administration for the treatment of progressive keratoconus in 2016. It is a relatively
Richa Agarwal, Parul Jain, Ritu Arora
doaj   +3 more sources

LOXL4, but not LOXL2, is the critical determinant of pathological collagen cross-linking and fibrosis in the lung. [PDF]

Sci Adv, 2023
Idiopathic pulmonary fibrosis is a progressive fibrotic disease characterized by excessive deposition of (myo)fibroblast produced collagen fibrils in alveolar areas of the lung.
Ma HY, Li Q, Wong WR, N'Diaye EN, Caplazi P, Bender H, Huang Z, Arlantico A, Jeet S, Wong A, Emson C, Brightbill H, Tam L, Newman R, Roose-Girma M, Sandoval W, Ding N.   +16 more
europepmc   +2 more sources

Fibromodulin Interacts with Collagen Cross-linking Sites and Activates Lysyl Oxidase. [PDF]

Journal of Biological Chemistry, 2016
The hallmark of fibrotic disorders is a highly cross-linked and dense collagen matrix, a property driven by the oxidative action of lysyl oxidase. Other fibrosis-associated proteins also contribute to the final collagen matrix properties, one of which is
Bihan, Dominique, Bonna, Arkadiusz, Farndale, Richard W, Kalamajski, Sebastian,, Lund University., Rubin, Kristofer,   +5 more
core   +6 more sources

Extracellular matrix with defective collagen cross-linking affects the differentiation of bone cells. [PDF]

PLoS ONE, 2018
Fibrillar type I collagen, the predominant organic component in bone, is stabilized by lysyl oxidase (LOX)-initiated covalent intermolecular cross-linking, an important determinant of bone quality.
Takako Ida, Masaru Kaku, Megumi Kitami, Masahiko Terajima, Juan Marcelo Rosales Rocabado, Yosuke Akiba, Masako Nagasawa, Mitsuo Yamauchi, Katsumi Uoshima   +8 more
doaj   +2 more sources

Recent advances in corneal collagen cross-linking

Indian Journal of Ophthalmology, 2017
Corneal collagen cross-linking has become the preferred modality of treatment for corneal ectasia since its inception in late 1990s. Numerous studies have demonstrated the safety and efficacy of the conventional protocol.
Gitansha Shreyas Sachdev, Mahipal Sachdev   +1 more
doaj   +2 more sources

Corneal collagen cross-linking for treating keratoconus. [PDF]

Cochrane Database of Systematic Reviews, 2015
BACKGROUND: Keratoconus is a condition of the eye that affects approximately 1 in 2000 people. The disease leads to a gradual increase in corneal curvature and decrease in visual acuity with consequent impact on quality of life.
Amissah-Arthur, Kwesi N, Bunce, Catey, Evans, Jennifer R, Hamada, Samer, Karim, Rushmia, McDonnell, Peter J, Patwary, Showrob, Sykakis, Evripidis   +7 more
core   +2 more sources

Collagen cross-linking beyond corneal ectasia: A comprehensive review [PDF]

Indian Journal of Ophthalmology
The history of corneal cross-linking (CXL) dates back to 2003 when some German scientists investigated possible treatments to harden the corneal structure to increase its resistance in ectatic corneal diseases.
Grigory A Osipyan, Husam Khraistin, Mohammad Jourieh   +2 more
doaj   +2 more sources

Corneal scarring after epithelium-off collagen cross-linking [PDF]

Indian Journal of Ophthalmology
Collagen cross-linking (CXL) is considered as a successful therapeutic approach for corneal conditions like keratoconus and corneal ectasia. Despite its efficacy in stabilizing these conditions, the occurrence of post-CXL scars remains a concern ...
Radhika Natarajan, Divya Giridhar
doaj   +2 more sources

Conjunctival Collagen Cross-Linking for the Treatment of Leaking Avascular Cystic Bleb [PDF]

Türk Oftalmoloji Dergisi
Trabeculectomy is a primary surgical procedure used to reduce intraocular pressure (IOP) in patients with glaucoma. Despite its effectiveness, it can lead to significant complications, including hypotony, choroidal effusion, blebitis, and bleb leaks ...
Ali Mert Koçer, Büşra Turpçuoğlu
doaj   +2 more sources

Abnormal Bone Collagen Cross‐Linking in Osteogenesis Imperfecta/Bruck Syndrome Caused by Compound Heterozygous PLOD2 Mutations

JBMR Plus, 2021
Bruck syndrome (BS) is a congenital disorder characterized by joint flexion contractures, skeletal dysplasia, and increased bone fragility, which overlaps clinically with osteogenesis imperfecta (OI).
C. Gistelinck, MaryAnn Weis, J. Rai, U. Schwarze, D. Niyazov, Kit M Song, P. Byers, D. Eyre   +7 more
semanticscholar   +1 more source