Standard versus transepithelial collagen cross-linking in the management of keratoconus
Delta Journal of Ophthalmology, 2018 Objective The aim of this study was to compare corneal collagen cross-linking (CXL) using either standard or transepithelial CXL. Patients and methods The study included 30 eyes of 18 patients with a mean age of 27.08 years.
Abd El-Magid M Tag El-Din +2 more
doaj +1 more source
Journal of Functional BiomaterialsThe cross-linking process of collagen is one of the more important ways to improve the mineralization ability of collagen. However, the regulatory effect of dynamic cross-linking on biomineralization in vitro remains unclear.
Ziyao Geng +4 more
doaj +1 more source
Double contact lens-assisted corneal cross-linking in ultrathin corneas with keratoconus
Saudi Journal for Health Sciences, 2018 Aims: This study aimed to evaluate the safety and effectiveness of double contact lens-assisted corneal cross-linking (CXL) in keratoconus patients with very thin corneas.
Abdulrahman M Alamri
doaj +1 more source
Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking [PDF]
International Journal of Ophthalmology, 2017 This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL® system, Waltham, MA, USA) over one year of follow-up.
Alberto Artola +4 more
doaj +1 more source
Resistance of corneal RFUVA-cross-linked collagens and small leucine-rich proteoglycans to degradation by matrix metalloproteinases [PDF]
, 2013 Purpose. Extracellular matrix metalloproteinases (MMPs) are thought to play a crucial role in corneal degradation associated with the pathological progression of keratoconus.
Conrad, Gary W. +4 more
core +2 more sources
Results of Accelerated Local Cross-Linking in Keratoconus
Oftalʹmologiâ, 2023 Objective of the study. To analyze the effectiveness of accelerated local corneal cross linking in the treatment of keratoconus (KC). Patients and methods.
H. Khraistin +4 more
doaj +1 more source
The process of EDC-NHS Cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment. [PDF]
, 2015 We describe the production of collagen fibre bundles through a multi-strand, semi-continuous extrusion process. Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide), NHS (N-hydroxysuccinimide) combination was considered.
Best, SM +5 more
core +2 more sources
Preferential sites for intramolecular glucosepane cross-link formation in type I collagen: A thermodynamic study [PDF]
, 2015 The extracellular matrix (ECM) undergoes progressive age-related stiffening and loss of proteolytic digestibility due to an increase in concentration of advanced glycation end products (AGEs).
Birch, H. L. +3 more
core +2 more sources
In Silico Modeling of the Rheological Properties of Covalently Cross-Linked Collagen Triple Helices [PDF]
, 2016 Biomimetic hydrogels based on natural polymers are a promising class of biomaterial, mimicking the natural extra-cellular matrix of biological tissues and providing cues for cell attachment, proliferation, and differentiation. With a view to providing an
Alberts B. +7 more
core +2 more sources
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source