Results 51 to 60 of about 4,668,535 (288)
Corneal melting after collagen cross-linking for keratoconus: a case report
Journal of Medical Case Reports, 2011 Introduction Corneal collagen cross-linking is a rather new technique that uses riboflavin and ultraviolet A light for collagen fiber stabilization in keratoconus corneas.
Zissimopoulos Athanassios +4 more
doaj +1 more source
Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix
FEBS Letters, EarlyView.The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual +3 more
wiley +1 more source
The outcome of corneal collagen cross-linking in progressive keratoconus: A 24-month follow-up
Kerala Journal of Ophthalmology, 2023 Purpose: The purpose of this study is to evaluate the effect of corneal collagen cross-linking on visual acuity and corneal parameters like keratometry and pachymetry.
A C Seena +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Bovine pericardium based non-cross linked collagen matrix for successful root coverage, a clinical study in human [PDF]
, 2012 Introduction: The aim of this study was to clinically assess the capacity of a novel bovine pericardium based, non-cross linked collagen matrix in root coverage. Methods: 62 gingival recessions of Miller class I or II were treated.
Sculean Anton +21 more
core +3 more sources
Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma.
PLoS ONE, 2011 PurposeTo determine the effect of Ultraviolet-A collagen cross-linking with hypo-osmolar and iso-osmolar riboflavin solutions on stromal collagen ultrastructure in normal and keratoconus ex vivo human corneas.MethodsUsing small-angle X-ray scattering ...
Sally Hayes +12 more
doaj +1 more source
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Accelerated corneal collagen cross-linking should be modified
, 2014 George D Kymionis,1,2 Konstantinos I Tsoulnaras11Vardinoyiannion Eye Institute of Crete, Faculty of Medicine, University of Crete, Heraklion, Crete, Greece; 2Bascom Palmer Eye Institute, University of Miami, Miller School of Medicine, Miami, FL,
Kymionis GD +3 more
core +1 more source
Cross-linking in type IV collagen [PDF]
Biochemical Journal, 1984 Type IV collagen could not be extracted from human placenta using 6M-urea containing 10mM-dithiothreitol, indicating that the type IV molecule is stabilized within the basement membrane by covalent cross-links. However, various forms of type IV collagen molecule were extractable by means of increasingly severe proteolytic conditions.
A J, Bailey, T J, Sims, N, Light
openaire +2 more sources