The process of EDC-NHS Cross-linking of reconstituted collagen fibres increases collagen fibrillar order and alignment. [PDF]
, 2015 We describe the production of collagen fibre bundles through a multi-strand, semi-continuous extrusion process. Cross-linking using an EDC (1-ethyl-3-(3-dimethylaminopropyl)carbodiimide), NHS (N-hydroxysuccinimide) combination was considered.
Best, SM +5 more
core +2 more sources
Journal of Functional BiomaterialsThe cross-linking process of collagen is one of the more important ways to improve the mineralization ability of collagen. However, the regulatory effect of dynamic cross-linking on biomineralization in vitro remains unclear.
Ziyao Geng +4 more
doaj +1 more source
Standard versus transepithelial collagen cross-linking in the management of keratoconus
Delta Journal of Ophthalmology, 2018 Objective The aim of this study was to compare corneal collagen cross-linking (CXL) using either standard or transepithelial CXL. Patients and methods The study included 30 eyes of 18 patients with a mean age of 27.08 years.
Abd El-Magid M Tag El-Din +2 more
doaj +1 more source
Results of Accelerated Local Cross-Linking in Keratoconus
Oftalʹmologiâ, 2023 Objective of the study. To analyze the effectiveness of accelerated local corneal cross linking in the treatment of keratoconus (KC). Patients and methods.
H. Khraistin +4 more
doaj +1 more source
In Silico Modeling of the Rheological Properties of Covalently Cross-Linked Collagen Triple Helices [PDF]
, 2016 Biomimetic hydrogels based on natural polymers are a promising class of biomaterial, mimicking the natural extra-cellular matrix of biological tissues and providing cues for cell attachment, proliferation, and differentiation. With a view to providing an
Alberts B. +7 more
core +2 more sources
Double contact lens-assisted corneal cross-linking in ultrathin corneas with keratoconus
Saudi Journal for Health Sciences, 2018 Aims: This study aimed to evaluate the safety and effectiveness of double contact lens-assisted corneal cross-linking (CXL) in keratoconus patients with very thin corneas.
Abdulrahman M Alamri
doaj +1 more source
Clinical outcomes at one year following keratoconus treatment with accelerated transepithelial cross-linking [PDF]
International Journal of Ophthalmology, 2017 This study evaluated the clinical outcomes in keratoconus corneas following accelerated transepithelial corneal collagen cross-linking (CXL) (Avedro KXL® system, Waltham, MA, USA) over one year of follow-up.
Alberto Artola +4 more
doaj +1 more source
Structural and functional analysis of two small leucine-rich repeat proteoglycans, fibromodulin and chondroadherin. [PDF]
, 2017 The small leucine-rich proteoglycans (SLRPs) are important regulators of extracellular matrix assembly and cell signalling. We have determined crystal structures at ~2.2Å resolution of human fibromodulin and chondroadherin, two collagen-binding SLRPs ...
Bihan, Dominique +5 more
core +1 more source
Riboflavin/UVA collagen cross-linking-induced changes in normal and keratoconus corneal stroma.
PLoS ONE, 2011 PurposeTo determine the effect of Ultraviolet-A collagen cross-linking with hypo-osmolar and iso-osmolar riboflavin solutions on stromal collagen ultrastructure in normal and keratoconus ex vivo human corneas.MethodsUsing small-angle X-ray scattering ...
Sally Hayes +12 more
doaj +1 more source
Effect of Low-Temperature Plasma Jet on Thermal Stability and Physical Structure of Type I Collagen [PDF]
, 2012 This work is devoted to the characterization of type I collagen treated by a low-temperature plasma jet generated in ambient air to determine whether the resulting fibrous material is structurally preserved or reinforced.
Dandurand, Jany +6 more
core +3 more sources