Results 91 to 100 of about 2,661,550 (300)

Functionalized collagen-based biomaterials via self-assembly: implications for gastrointestinal health

open access: yesCollagen and Leather
Collagen, one of the most abundant proteins in human physiology, maintains the morphology and structure of skin and tissues, serving as an important raw material for the repair of damaged tissues.
Qin Ma   +7 more
doaj   +1 more source

Facial Cosmetic Therapy Use Among Patients With Systemic Sclerosis: An Australian Cohort Study

open access: yesArthritis Care &Research, EarlyView.
Objective Systemic sclerosis (SSc) is associated with numerous facial manifestations for which patients may engage in cosmetic therapies. It is unclear how patients with SSc use these therapies. This study sought to characterize patient engagement and experiences with cosmetic therapies for SSc‐related and non‐SSc–related facial changes.
Zachary Warren   +11 more
wiley   +1 more source

Collagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1+ macrophages prevents cigarette smoke-induced emphysema and loss of airway function

open access: yesFrontiers in Immunology
IntroductionCollagen is essential for maintaining lung structure and function and its remodeling has been associated with respiratory diseases including chronic obstructive pulmonary disease (COPD).
Yinebeb Mezgebu Dagnachew   +25 more
doaj   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

open access: yesAdvanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon   +5 more
wiley   +1 more source

Lysyl Oxidase Reduces Neutrophil Extravasation in Response to P. aeruginosa in an Infection‐on‐a‐Chip Model

open access: yesAdvanced NanoBiomed Research
Neutrophils are crucial players in the fight against infections. Unfortunately, dysregulated neutrophil function contributes to the pathogenesis of diseases, including cancer, fibrosis, and atherosclerosis, that leave those afflicted vulnerable to severe
Christopher J. Calo   +7 more
doaj   +1 more source

Plasma membrane overgrowth causes fibrotic collagen accumulation and immune activation in Drosophila adipocytes

open access: yeseLife, 2015
Many chronic diseases are associated with fibrotic deposition of Collagen and other matrix proteins. Little is known about the factors that determine preferential onset of fibrosis in particular tissues.
Yiran Zang   +7 more
doaj   +1 more source

Reversible Tuning of Multiple Molecular Kinking for Stem Cell Regulation In Vivo

open access: yesAdvanced Functional Materials, EarlyView.
In this work, we introduce the novel concept of background component‐free “multiple kinks” material platform composed solely of liganded multiple kink‐bearing molecules as a strategy for dynamic biomaterial design. Tri‐kink molecules enable effective near‐infrared light‐triggered ligand masking and visible light‐triggered ligand exposure, thereby ...
Kanghyeon Kim   +28 more
wiley   +1 more source

Collagen in arterial walls : Biomechanical aspects

open access: yes, 2008
This chapter is written with an emphasis on the biomechanical role of collagen in normal and diseased arterial walls, its structural quantification and its consideration in material models including phenomena such as growth and remodeling.
Holzapfel, Gerhard A.,
core   +1 more source

An Integrated Oxygen‐Supplying Device and Predictive Multiphysics Model for Extended Ambient Transport of Insulin‐Producing Cells

open access: yesAdvanced Functional Materials, EarlyView.
Cell therapies typically rely on cold‐chain logistics and cryopreservation, limiting access and compromising cell quality. Here, a dual‐chamber device separates an oxygen‐supplying chamber from a hyaluronic acid cargo chamber, sustaining oxygen delivery for over 70 h and enabling ambient‐temperature shipment.
Daniel A. Domingo‐Lopez   +9 more
wiley   +1 more source

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