Results 81 to 90 of about 514,386 (288)

Endogenous musculoskeletal tissue engineering - a focused perspective [PDF]

, 2012
Two major difficulties facing widespread clinical implementation of existing Tissue Engineering (TE) strategies for the treatment of musculoskeletal disorders are (1) the cost, space and time required for ex vivo culture of a patient’s autologous cells ...
Adam, Clayton
core   +2 more sources

Raman Microscopy at the Organic–Inorganic Interfaces in Human Calcified Aortic Valves Shows the Co‐Existence of Whitlockite Crystals and Carbonated Hydroxyapatite‐Mineralized Collagen Fibrils

Advanced Functional Materials, EarlyView.
This study advances our understanding of aortic valve stenosis by capturing spatially resolved chemical and structural changes at the nanoscale. The findings highlight the potential of combined Raman and electron microscopy for understanding calcification mechanisms across diverse tissue types.
Robin H. M. Van der Meijden, Carolien T. A Kuster, Amber van Broekhoven, Raphaela Allgayer, Luco Rutten, Rona Roverts, Marta Cerruti, Elena Macías‐Sánchez, Jan Hein Cornel, Salloua el Messaoudi, Anat Akiva, Nico Sommerdijk   +11 more
wiley   +1 more source

Acquired perforating dermatosis in the setting of hepatocellular carcinoma

JAAD Case Reports, 2021
Reinaldo Tovo Filho, MD, PhD, Silmara da Costa Pereira Cestari, MD, PhD, Isabella Zurita Dehó, MD, Reinaldo Falavigna Tovo, PhD, Gabriela Franco Marques, MD, PhD, Ivana Diniz Lírio, MD, Mariana Petaccia de Macedo, MD   +6 more
doaj   +1 more source

Developing an Injectable Nanofibrous Extracellular Matrix Hydrogel With an Integrin αvβ3 Ligand to Improve Endothelial Cell Survival, Engraftment and Vascularization

Frontiers in Bioengineering and Biotechnology, 2020
Endothelial cell (EC) transplantation via injectable collagen hydrogel has received much attention as a potential treatment for various vascular diseases.
Dake Hao, Dake Hao, Ruiwu Liu, Kewa Gao, Kewa Gao, Chuanchao He, Siqi He, Siqi He, Cunyi Zhao, Gang Sun, Diana L. Farmer, Diana L. Farmer, Alyssa Panitch, Alyssa Panitch, Kit S. Lam, Aijun Wang, Aijun Wang, Aijun Wang   +17 more
doaj   +1 more source

Gene polymorphisms in primary biliary cirrhosis: association with the disease and hepatic osteopathy [PDF]

, 2007
Genetic factors have been implicated in the pathogenesis of osteoporosis, a common disorder in primary biliary cirrhosis (PBC). Estrogen receptor-alpha gene (ER- ), vitamin-D-receptor gene (VDR) and IL-1-receptor-antagonist gene (IL-1RN) are all ...
Bajnok, Éva, Ferenci, Péter, Lakatos, Péter, Lakatos, Péter László, Szalay, Ferenc, Takács, István, Willheim-Polli, Claudia   +6 more
core  

Cardiac‐Derived ECM Microspheres for Enhanced hiPSC‐CMs Maturation

Advanced Functional Materials, EarlyView.
Cardiac extracellular matrix microspheres derived from decellularized porcine heart provide a biomimetic 3D microenvironment for human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs). This platform supports short‐ and long‐term culture, enhances structural organization, and promotes electrophysiological and functional maturation of ...
Jiazhu Xu, Joel Aboagye, Marcella Edwards, Nick Rogozinski, Yufeng Wen, Angello Huerta Gomez, Zui Pan, Ge Zhang, Huaxiao Yang, Yi Hong   +9 more
wiley   +1 more source

Functionalized collagen-based biomaterials via self-assembly: implications for gastrointestinal health

Collagen and Leather
Collagen, one of the most abundant proteins in human physiology, maintains the morphology and structure of skin and tissues, serving as an important raw material for the repair of damaged tissues.
Qin Ma, Yuanmeng He, Yunxiang He, Yue Wu, Qinling Liu, Yulin Guan, Lie Yang, Junling Guo   +7 more
doaj   +1 more source

Collagen deposition in lung parenchyma driven by depletion of interstitial Lyve-1+ macrophages prevents cigarette smoke-induced emphysema and loss of airway function

Frontiers in Immunology
IntroductionCollagen is essential for maintaining lung structure and function and its remodeling has been associated with respiratory diseases including chronic obstructive pulmonary disease (COPD).
Yinebeb Mezgebu Dagnachew, Yinebeb Mezgebu Dagnachew, Yinebeb Mezgebu Dagnachew, Hwee Ying Lim, Hwee Ying Lim, Liao Wupeng, Liao Wupeng, Sheau Yng Lim, Sheau Yng Lim, Sheng Jie Natalie Lim, Sheng Jie Natalie Lim, Chung Hwee Thiam, Chung Hwee Thiam, Shu Wen Tan, Shu Wen Tan, Joan Lau Joo Eng, Joan Lau Joo Eng, Dan Mei, Syaza Hazwany Mohammad Azhar, Wei Siong Ong, Qi Hui Caris Tan, Wai-Shiu Fred Wong, Wai-Shiu Fred Wong, Wai-Shiu Fred Wong, Veronique Angeli, Veronique Angeli   +25 more
doaj   +1 more source

Urinary CE-MS peptide marker pattern for detection of solid tumors [PDF]

, 2018
Urinary profiling datasets, previously acquired by capillary electrophoresis coupled to mass-spectrometry were investigated to identify a general urinary marker pattern for detection of solid tumors by targeting common systemic events associated with ...
Belczacka, Iwona, Frantzi, Maria, Jankowski, Vera, Latosinska, Agnieszka, Merseburger, Axel S., Metzger, Jochen, Mischak, Harald, Siwy, Justyna, Vlahou, Antonia   +8 more
core   +2 more sources

3D‐Printed Porous Hydroxyapatite Formed via Enzymatic Mineralization

Advanced Functional Materials, EarlyView.
Bone combines lightness, strength, and the ability to heal, inspiring new materials design. This work introduces a room‐temperature, enzyme‐mediated 3D printing method to create porous hydroxyapatite scaffolds. The process avoids energy‐intensive sintering, preserves bioactivity, and allows control over porosity and mineralization.
Francesca Bono, Anna Puiggalí‐Jou, Greta Cocchi, Mariangela Miccoli, Katharina Maniura‐Weber, Marcy Zenobi‐Wong, Esther Amstad   +6 more
wiley   +1 more source