Results 211 to 220 of about 140,913 (263)
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Binding domain for laminin on type IV collagen
Biochemical and Biophysical Research Communications, 1985Binding of type IV collagen to laminin was studied by attaching one member of the ligand pair to a solid phase. When laminin was bound to a solid phase, type IV collagen exhibited saturable binding. Digestion of type IV collagen with high concentrations of pepsin destroyed the laminin binding activity.
C N, Rao, I M, Margulies, L A, Liotta
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The life cycle of type IV collagen
Matrix BiologyType IV collagen is a large triple helical molecule that forms a covalently cross-linked network within basement membranes (BMs). Type IV collagen networks play key roles in mechanically supporting tissues, shaping organs, filtering blood, and cell signaling.
Sandhya Srinivasan, David R. Sherwood
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Collagen type IV in epithelial tumours of colon
Acta Histochemica, 2002Collagen type IV in the lamina propria mucosae is one of the main components of the basement membrane of normal and transitional colon mucosa. The aim of the present study was to assess the use of anti-collagen type IV antibodies in the evaluation of biological activity of epithelial tumours of the colon.
Stefan, Galbavý +8 more
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A nonradioactive assay for type IV collagen degradation
Analytical Biochemistry, 1990A sensitive assay for type IV collagen degradation using an avidin-biotin sandwich technique is described. Biotinylated type IV collagen is allowed to bind to an avidin-coated microtiter plate. The solution to be assayed is incubated with the biotinylated collagen bound to the avidin plate.
M J, Wilkinson, R L, Cohen, M A, Shuman
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The Involvement of Type IV Collagen in Goodpasture's Syndromea
Annals of the New York Academy of Sciences, 1985Goodpasture's syndrome, involving lung and kidney, is considered to be caused by autoantibodies to basement membranes. This paper has described the isolation and identification of the antigen, which is isolated from collagenase digests of glomerular basement membrane, as a monomer protein of 26,000 daltons and two dimers of about 50,000 daltons ...
J, Wieslander, D, Heinegård
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Type IV collagenase and immunostaining of type IV collagen in human thyroid tumors
Auris Nasus Larynx, 2000Required stages in the processes of malignant tumor invasion and metastasis are known to include the destruction of cell stroma and vascular basement membrane. It has been suggested that type IV collagenase can degrade type IV collagen, a main component of basement membrane.
T, Kusunoki +5 more
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The presence of EC collagen and type IV collagen in bovine Descemet's membranes
Biochemical and Biophysical Research Communications, 1983When bovine Descemet's membranes (DMs) were characterized after limited pepsinization the major component in DM was found to be endothelial cell (EC) collagen. Phenol extractions of the undigested pepsin residue recovered only type IV collagen. This study provides evidence that EC collagen may be produced by corneal endothelial cells in vivo.
U, Labermeier, M C, Kenney
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Type IV collagen and diabetic kidney disease
Nature Reviews Nephrology, 2019A new genome-wide association study of patients with type 1 diabetes mellitus reveals novel loci that are associated with the development of diabetic kidney disease. The most significant of these loci encodes the α3 chain of type IV collagen, which is an important component of the glomerular basement membrane.
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Collagen and its derivatives: From structure and properties to their applications in food industry
Food Hydrocolloids, 2022Baocai Xu, Kai Zhou, Wendi Zhang
exaly