Type IV collagen reduces MUC5AC secretion in the lungs of ovalbumin-sensitized mice [PDF]
Frontiers in Pharmacology, 2022 Mucin 5AC (MUC5AC) is excessively secreted in the respiratory tract of patients with asthma. Suppressing this secretion is important for improving the air passages, which facilitates easy breathing.
Jun Iwashita +3 more
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Prognostic Value of Stromal Type IV Collagen Expression in Small Invasive Breast Cancers [PDF]
Frontiers in Molecular Biosciences, 2022 Breast cancer is the most common cause of cancer death among women worldwide. Localized breast cancer can be cured by surgery and adjuvant therapy, but mortality remains high for tumors that metastasize early.
Malin Jansson +10 more
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The life cycle of type IV collagen. [PDF]
Matrix BiolType IV collagen is a large triple helical molecule that forms a covalently cross-linked network within basement membranes (BMs). Type IV collagen networks play key roles in mechanically supporting tissues, shaping organs, filtering blood, and cell signaling.
Srinivasan S, Sherwood DR.
europepmc +3 more sources
Escherichia coli induced matrix metalloproteinase-9 activity and type IV collagen degradation is regulated by progesterone in human maternal decidual [PDF]
BMC Pregnancy and ChildbirthBackground Escherichia coli (E. coli) is one of the main bacteria associated with preterm premature rupture of membranes by increasing pro-matrix metalloproteinase 9 (proMMP-9) and degradation of type IV collagen in human feto-maternal interface (HFMi ...
Gerardo Bautista-Bautista +9 more
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Morphometric analysis of the human endoneurial extracellular matrix components during aging [PDF]
Archives of Biological Sciences, 2021 The aim of this study was to analyze the expression of extracellular matrix (ECM) proteins in human endoneurium during aging. We harvested 15 cadaveric sural nerves, distributed in 3 age groups (I: 25-44, II: 45-64, III: 65-86 years old).
Kundalić Braca K. +8 more
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Type IV Collagen Mutations in Familial IgA Nephropathy [PDF]
Kidney International Reports, 2020 Yifu Li +17 more
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Expression of collagen type IV in human kidney during prenatal development [PDF]
Vojnosanitetski Pregled, 2022 Background/Aim. Type IV collagen belongs to the group of nonfibrillar collagens and is an important component of the basement membranes, where it accounts for approximately 50% of its structural elements.
Petrović Vladimir +5 more
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Journal of Orofacial Sciences, 2021 Introduction: Cyclooxygenase 2 (COX-2) expression in oral potentially malignant disorders (OPMDs) such as oral submucous fibrosis (OSMF) and oral squamous cell carcinomas (OSCCs) has revealed inconclusive reports.
P. Sharada +4 more
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Specifics of type IV collagen expression in basal cell skin carcinoma
Alʹmanah Kliničeskoj Mediciny, 2020 Rationale: Type IV collagen is the main component of the basal membrane ensuring its integrity. Basal membrane destruction is associated with absent type IV collagen expression being directly related to an increased tumor invasion risk.
A. N. Khlebnikova +4 more
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Pattern of collagen IV expression in glomerular and mesenchymal basement membrane during fetal and postnatal period of Balb/c Mice [PDF]
Journal of Cell and Molecular Research, 2009 Basement membrane of glomerular mesangium (BMG) is a thin membrane which helps to support the capillary loops in a renal glomerulus and type IV collagen is require for complete BM formation during glomerulogenesis. In this investigation specific antibody
Mohammad Reza Nikravesh +6 more
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