Results 21 to 30 of about 140,904 (262)

Modulation of C1-Inhibitor and Plasma Kallikrein Activities by Type IV Collagen

International Journal of Biomaterials, 2012
The contact system of coagulation can be activated when in contact with biomaterials. As collagen is being tested in novel biomaterials in this study, we have investigated how type IV collagen affects plasma kallikrein and C1-inhibitor.
Sriram Ravindran, Marc Schapira, Philip A. Patston   +2 more
doaj   +1 more source

BIOCHEMICAL ASPECTS OF COLLAGEN TYPE IV METABOLISM IN PATIENTS WITH GASTROESOPHAGEAL REFLUX DISEASE AND/OR OBSTRUCTIVE SLEEP APNEA/HYPOPNEA SYNDROME

Žurnal Grodnenskogo Gosudarstvennogo Medicinskogo Universiteta, 2019
Background. Gastroesophageal reflux disease (GERD) and obstructive sleep apnea/hypopnea syndrome (OSAHS) seem to be comorbid conditions. However, pathogenetic interactions between these conditions are not completely researched. Aim of the study.
Shaukovich Y., Shyshko V., Darashenka Y.
doaj   +1 more source

Laminin and type IV collagen in the human testis [PDF]

International Journal of Andrology, 1985
Specimens of normal human testis and biopsies from testes with Sertoli‐cell‐only syndrome in which the seminiferous tubules had a remarkably thickened lamina propria, were investigated immunohistochemically using specific antibodies against human laminin and human type IV collagen.
P P, Pöllänen, M, Kallajoki, L, Risteli, J, Risteli, J J, Suominen   +4 more
openaire   +2 more sources

Peran Lipopolisakarida Helicobacter pylori terhadap Aktivitas Neutrofil pada Penderita Infark Miokard Akut melalui Degradasi Kolagen Tipe IV

Majalah Kardiologi Indonesia, 2013
Matrix metalloproteases (MMPs) are proteolytic enzymes that play a criti-cal role in decreasing the stability of atherosclerotic plaque causing Acute Myocardial Infarction (AMI). In this process, degradation of type IV col-lagen as an important component
Djanggan Sargowo, I Ketut Gede Muliartha, Mudyawati Kamaruddin   +2 more
doaj   +1 more source

Type IV collagen-derived angiogenesis inhibitors [PDF]

Microvascular Research, 2007
The concept of anti-angiogenesis therapy was introduced by Judah Folkman in 1971 and since then, a plethora of pro- and anti-angiogenic factors have been identified. In the recent years, it has become clear that angiogenesis, the formation of new capillaries from a pre-existing capillary network, is highly regulated by the action of pro- and anti ...
Thomas M, Mundel, Raghu, Kalluri
openaire   +2 more sources

Serum Col3-4: A new type III and IV collagen biochemical marker of synovial tissue turnover in patients with rheumatoid arthritis

PLoS ONE, 2023
The objective of this study was to develop a serum biochemical marker of the degradation of type III and IV collagens, as an index of synovium turnover, and evaluate its performance in patients with rheumatoid arthritis (RA).
Evelyne Gineyts, Marjorie Millet, Olivier Borel, Frédéric Coutant, Jean-Charles Rousseau, Roland Chapurlat, Hubert Marotte, Patrick Garnero   +7 more
doaj   +2 more sources

Type IV Collagen in Hypertrophic Cardiomyopathy.

Japanese Heart Journal, 1994
Basement membrane of myocytes from patients with hypertrophic cardiomyopathy who died suddenly, seemed to be discontinuous by immunohistochemical methods. With the use of the sandwich immunoassay technique, we determined the frequency of type IV collagen and its influence on functional abnormality in 31 patients with hypertrophic cardiomyopathy and ...
OHSATO, Kazuo, SHIMIZU, Masami, SUGIHARA, Norihiko, INO, Hidekazu, YOSHIO, Hiroyuki, TAKAGI, Yoshinori, TAKEDA, Ryoyu   +6 more
openaire   +3 more sources

The clinical spectrum of type IV collagen mutations [PDF]

Human Mutation, 1997
Clinical manifestations of type IV collagen mutations can vary from the severe, clinically and genetically heterogeneous renal disorder, Alport syndrome, to autosomal dominant familial benign hematuria. The predominant form of Alport syndrome is X-linked; more than 160 different mutations have yet been identified in the type IV collagen alpha 5 chain ...
Lemmink, H.H., Schröder, C.H., Monnens, L.A.H., Smeets, H.J.M.   +3 more
openaire   +4 more sources

Type IV collagen reduces mucin 5AC secretion in three-dimensional cultured human primary airway epithelial cells

Biochemistry and Biophysics Reports, 2019
Mucin 5AC (MUC5AC) hypersecretion induces airway narrowing in patients with asthma, which leads to breathing problems. We investigated the regulation of MUC5AC secretion by extracellular matrix (ECM) proteins in human primary airway epithelial cells from
Yuho Ito, Jun Iwashita, Jun Murata
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source