Results 61 to 70 of about 8,720,014 (305)
Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Functional Imaging of Proteolysis: Stromal and Inflammatory Cells Increase Tumor Proteolysis
Molecular Imaging, 2003 The underlying basement membrane is degraded during progression of breast and colon carcinoma. Thus, we imaged degradation of a quenched fluorescent derivative of basement membrane type IV collagen (DQ-collagen IV) by living human breast and colon tumor ...
Mansoureh Sameni +3 more
doaj +1 more source
مجله كليه طب الكندي, 2016 Background: the difference in expression of type IV collagen in borderline tumors and ovarian carcinomas has been studied, but the association with adhesion molecules like CD44 have not gain enough interest.
Mohanad M. Abdul Ghany +2 more
doaj +1 more source
Type IV collagen-derived angiogenesis inhibitors [PDF]
Microvascular Research, 2007 The concept of anti-angiogenesis therapy was introduced by Judah Folkman in 1971 and since then, a plethora of pro- and anti-angiogenic factors have been identified. In the recent years, it has become clear that angiogenesis, the formation of new capillaries from a pre-existing capillary network, is highly regulated by the action of pro- and anti ...
Thomas M, Mundel, Raghu, Kalluri
openaire +2 more sources
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Type IV Collagen, Type IV Collagenase Activity and Ability of Cell Proliferation in Human Thyroid Tumours [PDF]
, 2002 BackgroundThe processes of malignant tumour invasion and metastasis are known to include the destruction of cell stroma and vascular basement membrane.
Tomura, Takanori +11 more
core +1 more source
FEBS Open Bio, EarlyView.UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová +2 more
wiley +1 more source
Secretion of Type IV Collagen by Keratinocytes of Human Adult [PDF]
, 1985 Secretion of type IV collagen by keratinocytes was studied by anti-type IV collagen immunoglobulin in pure keratinocyte culture of the human adult. The cultivated keratinocytes secreted type IV collagen into the space between skin collagen type I.
Gustav Asboe-Hansen +5 more
core +1 more source
Majalah Kardiologi Indonesia, 2013 Background. Index mortality of atherosclerotic very high. The research conducted by WHO in 1995 show 20% of IMA mortality caused by ath-erosclerotic. The new emerging risk factor infection is the Perviromonas gingivalis.
Ketut Muliartha +2 more
doaj +1 more source
MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis
FEBS Open Bio, EarlyView.MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss +7 more
wiley +1 more source