Results 211 to 220 of about 7,552,757 (294)

Considerations for drug trials in hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1095-1112, April 2025.
Abstract Hypertrophic cardiomyopathy (HCM) is a heterogeneous condition with potentially serious manifestations. Management has traditionally comprised therapies to palliate symptoms and implantable cardioverter‐defibrillators to prevent sudden cardiac death. The need for disease‐modifying therapies has been recognized for decades.
John P. Farrant   +17 more
wiley   +1 more source

Causal correlations between inflammatory proteins and heart failure: A two‐sample Mendelian randomization analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1374-1385, April 2025.
Abstract Aims Inflammation plays a critical role in both the development and progression of heart failure (HF), which is a leading cause of morbidity and mortality worldwide. However, the causality between specific inflammation‐related proteins and HF risk remains unclear.
Xian‐Guan Zhu   +9 more
wiley   +1 more source

Extravascular distribution of factor IX-review of experimental and clinical evidence, and relevance for hemophilia B replacement therapy. [PDF]

open access: yesRes Pract Thromb Haemost
Hermans C   +6 more
europepmc   +1 more source

Cross‐protective effect of a multicomponent fusion protein vaccine during a natural episode of Streptococcus zooepidemicus respiratory disease in ponies

open access: yesEquine Veterinary Journal, EarlyView.
Abstract Background Streptococcus equi subspecies zooepidemicus is a highly diverse opportunistic pathogen of horses, associated with respiratory disease and endometritis. Objectives To characterise S. zooepidemicus isolates recovered from young ponies during a natural episode of respiratory disease, and to determine if vaccination with Strangvac®, a ...
Romain Paillot   +8 more
wiley   +1 more source

Epidermolysis bullosa acquisita improved with use of dupilumab. [PDF]

open access: yesJAAD Case Rep
Raneses E   +3 more
europepmc   +1 more source

Measurement Tools for Radiation‐Induced Fibrosis in Head and Neck Cancer: A Systematic Review

open access: yesHead &Neck, EarlyView.
ABSTRACT Background Radiation‐induced fibrosis is a common, often debilitating late effect of head and neck cancer (HNC) treatment. An updated systematic review is needed to evaluate the reliability, validity, and clinical utility of fibrosis measurement tools.
Vanessa Helou   +11 more
wiley   +1 more source

Systemic clinical-grade recombinant decorin reduces disease burden and fibrosis in advanced recessive dystrophic epidermolysis bullosa. [PDF]

open access: yesMol Ther Adv
Gretzmeier C   +12 more
europepmc   +1 more source

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