Results 1 to 10 of about 21,965 (154)

Diagnostic potential of Type VII Collagen during oral carcinogenesis [PDF]

Journal of Applied Oral Science, 2023
Type VII collagen (Col7) is a major component of anchoring fibrils. Col7 plays a role in tumor development and aggressiveness of cutaneous squamous cell carcinoma of recessive dystrophic epidermolysis bullosa.
Sopee POOMSAWAT, Abdulshukor KARIYA, Thirayost NIMMANON, Theerachai KOSANWAT, Rachai JUENGSOMJIT, SANGUANSIN Sirima   +5 more
doaj   +5 more sources

Diagnosis of Epidermolysis Bullosa Acquisita: Multicentre Comparison of Different Assays for Serum Anti-type VII Collagen Reactivity [PDF]

Acta Dermato-Venereologica, 2021
Epidermolysis bullosa acquisita is a pemphigoid disease characterized by autoantibodies against type VII collagen. This study compared the sensitivity and specificity of 6 diagnostic assays: type VII collagen non-collagenous domains enzyme-linked ...
Maike M. Holtsche, Nina van Beek, Takashi Hashimoto, Giovanni Di Zenzo, Detlef Zillikens, Catherine Prost-Squarcioni, Matthias Titeux, Alain Hovnanian, Enno Schmidt, Stephanie Goletz   +9 more
doaj   +2 more sources

Anti-Type VII Collagen Antibodies Are Identified in a Subpopulation of Bullous Pemphigoid Patients With Relapse [PDF]

Frontiers in Immunology, 2018
Bullous pemphigoid (BP) is an autoimmune bullous skin disease characterized by anti-BP180 and anti-BP230 autoantibodies (AAbs). Mucous membrane involvement is an uncommon clinical feature of BP which may evoke epidermolysis bullosa acquisita, another ...
Delphine Giusti, Delphine Giusti, Grégory Gatouillat, Grégory Gatouillat, Sébastien Le Jan, Julie Plée, Julie Plée, Philippe Bernard, Philippe Bernard, Frank Antonicelli, Frank Antonicelli, Bach-Nga Pham, Bach-Nga Pham   +12 more
doaj   +2 more sources

Structural and biophysical characterization of the type VII collagen vWFA2 subdomain leads to identification of two binding sites [PDF]

FEBS Open Bio, 2020
Type VII collagen is an extracellular matrix protein, which is important for skin stability; however, detailed information at the molecular level is scarce.
Jan M. Gebauer, Florian Flachsenberg, Cordula Windler, Barbara Richer, Ulrich Baumann, Karsten Seeger   +5 more
doaj   +2 more sources

Recombinant humanized type VII collagen for skin repair and regeneration: prospects for reconstructing the dermal-epidermal junction [PDF]

Frontiers in Medicine
Type VII collagen (Col VII) is a key component of the anchoring fibrils at the dermal-epidermal junction (DEJ). It plays a crucial role in maintaining stable adhesion between the epidermis and dermis, promoting wound re-epithelialization, and ensuring ...
Yanyan Lin, Jie Zheng, Xiaobin Lan
doaj   +2 more sources

Type VII Collagen Expression in the Human Vitreoretinal Interface, Corpora Amylacea and Inner Retinal Layers. [PDF]

PLoS ONE, 2015
Type VII collagen, as a major component of anchoring fibrils found at basement membrane zones, is crucial in anchoring epithelial tissue layers to their underlying stroma.
Bart Wullink, Hendri H Pas, Roelofje J Van der Worp, Roel Kuijer, Leonoor I Los   +4 more
doaj   +2 more sources

Accelerated Type VII collagen turnover in systemic sclerosis patients, reflected by serological neo-epitope fragment biomarkers [PDF]

Arthritis Research & Therapy
Background Systemic sclerosis (SSc) is a rare autoimmune disease characterized by microvasculopathy, autoantibody production, and fibrosis of the skin and internal organs.
Yi He, Jannie M B Sand, Satoshi Kubo, Naoaki Ohkubo, Yusuke Miyazaki, Morten Karsdal, Yoshiya Tanaka, Anne-Christine Bay-Jensen   +7 more
doaj   +2 more sources

Detection of Type VII collagen in odontogenic keratocyst: An immunohistochemical study. [PDF]

J Clin Exp Dent, 2019
Separation of the epithelial lining from the underlying connective tissue wall has been a frequently observed and unique feature in odontogenic keratocysts (OKC), but not in other odontogenic cysts nor neoplasms. No study on OKC has been reported evaluating the role of type VII Collagen, the anchoring fibrils, which function in stabilising the ...
Cota JE, Spadigam A, Dhupar A.
europepmc   +4 more sources

A novel deletion and two recurrent substitutions on type VII collagen gene in seven Iranian patients with epidermolysis bullosa [PDF]

Iranian Journal of Basic Medical Sciences, 2016
Objective(s): Epidermolysis bullosa is one of the most important series of mechano-bullous heritable skin disorders which is categorized into four major types according to the layer that bullae forms within basement membrane zone.
Armita Kakavand Hamidi, Mohammad Moghaddam, Nasim Hatamnejadian, Ahmad Ebrahimi   +3 more
doaj   +2 more sources

Childhood epidermolysis bullosa acquisita: Confirmation of diagnosis by skin deficient in Type VII Collagen, enzyme-linked immunosorbent assay, and immunoblotting [PDF]

Indian Journal of Dermatology, 2016
Epidermolysis bullosa acquisita (EBA) is an acquired subepidermal bullous disorder characterized by autoantibodies against Type VII collagen. It usually affects adults; childhood EBA is rare. We describe a 10-year-old girl presenting with recurrent tense
Nupur Goyal, Raghavendra Rao, C Balachandran, Sathish Pai, Balbir S Bhogal, Enno Schmidt, Detlef Zillikens   +6 more
doaj   +2 more sources