Results 11 to 20 of about 7,552,757 (287)

Type VII collagen in Alport syndrome [PDF]

Nephrology Dialysis Transplantation, 2007
Absence or segmental distribution of the alpha5(IV) collagen chain along the epidermal basement membrane (EBM) is diagnostic of X-linked Alport syndrome (X-AS), but the typical morphologic alterations usually observed along the glomerular basement membrane (GBM) are lacking. However, several differences in protein composition exist between GBM and EBM,
GIANNAKAKIS, Konstantinos, L. Massella, D. Grassetti, F. Dotta, M. Perez, A. O. Muda   +5 more
core   +6 more sources

The Epidermolysis Bullosa Acquisita Antigen (Type VII Collagen) is Present in Human Colon and Patients with Crohn's Disease have Autoantibodies to Type VII Collagen [PDF]

Journal of Investigative Dermatology, 2002
Epidermolysis bullosa acquisita is an autoimmune blistering disease of the skin characterized by IgG autoantibodies against type VII collagen. Systemic diseases are often associated with epidermolysis bullosa acquisita, Crohn's disease being the most frequent.
Chen, Mei, O'Toole, Edel A., Sanghavi, Jigisha, Woodley, David T., Mahmud, Nasir, Kelleher, Dermot, Weir, Donald, Fairley, Janet A.   +7 more
openaire   +5 more sources

Laminin 5 Binds the NC-1 Domain of Type VII Collagen [PDF]

Journal of Cell Biology, 1997
Mutational analyses of genes that encode components of the anchoring complex underlying the basolateral surface of external epithelia indicate that this structure is the major element providing for resistance to external friction. Ultrastructurally, laminin 5 (α3β3γ2; a component of the anchoring filament) appears as a thin filament bridging the ...
Patricia Rousselle, Florence RUGGIERO, Douglas R Keene   +2 more
exaly   +4 more sources

Immunohistochemical expression of collagen type VII antibody in the human fetal temporomandibular joint discs [PDF]

Einstein (São Paulo), 2007
Objective: To study the articular disc morphology and to analyze theimmunohistochemical expression of the type VII collagen marker inhuman fetal temporomandibular joint discs at different gestational ages.Methods: Twenty human fetal temporomandibular ...
Luís Otávio Carvalho de Morais, Fábio Redivo Lodi, Sergio Ricardo Marques, Celina Tizuko Fijiyama Oshima, João Antão Fernandes Júnior, Ricardo Luiz Smith, Luís Garcia Alonso   +6 more
doaj   +1 more source

The potential role of collagen type VII in breast cancer proliferation

Cancer Cell International
Background Breast cancer is the most common cancer in women. Cancer cells can persist in a prolonged dormant state for years without any clinical evidence of disease creating an urgent need to better understand the molecular mechanisms leading to relapse.
Sergio Pérez-Díaz, Jessica Lindberg, Luis Oliveros Anerillas, Paul J. Kingham, Malin Sund, Gunilla Rask, Johan Svensson, Malin Jansson, Rebecca Wiberg   +8 more
doaj   +5 more sources

CRISPR/Cas9-Mediated Generation of COL7A1-Deficient Keratinocyte Model of Recessive Dystrophic Epidermolysis Bullosa [PDF]

Cell Journal, 2023
Objective: Recessive dystrophic epidermolysis bullosa (RDEB) is a genetic skin fragility and ultimately lethal blisteringdisease caused by mutations in the COL7A1 gene which is responsible for coding type VII collagen.
Farzad Alipour, Mana Ahmadraji, Elham Yektadoost, Parvaneh Mohammadi, Hossein Baharvand, Mohsen Basiri   +5 more
doaj   +1 more source

Immunohistochemical localization of collagen types I and VI in human skin wounds [PDF]

, 1996
A total of 74 human skin wounds were investigated and collagen types I and VI were localized in the wound area by immunohistochemistry. Collagen type I appeared in the form of ramifying string-like structures after approximately 5–6 days, but positive ...
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Wilske, J., Betz, P.   +5 more
core   +1 more source

Case Report: Diagnostic and Therapeutic Challenges in Severe Mechanobullous Epidermolysis Bullosa Acquisita

Frontiers in Immunology, 2022
Collagen VII is the main constituent of the anchoring fibrils, important adhesive structures that attach the epidermis to the dermal extracellular matrix.
Franziska Schauer, Alexander Nyström, Manfred Kunz, Stefanie Hübner, Sarah Scholl, Ioannis Athanasiou, Svenja Alter, Judith Fischer, Cristina Has, Dimitra Kiritsi   +9 more
doaj   +1 more source

The time-dependent rearrangement of the epithelial basement membrane in human skin wounds [PDF]

, 1992
In 62 human skin wounds (surgical wounds, stab wounds and lacerations after surgical treatment) we analyzed the immunohistochemical localization of collagen IV in the epithelial basement membrane.
Penning, R., Eisenmenger, Wolfgang, Nerlich, A., Tübel, J., Wilske, J., Betz, P., Wiest, I.   +6 more
core   +1 more source

Medical cell technologies for treatment of patients suffering from recessive dystrophic epidermolysis bullosa. Method of intracutaneous administration of fibroblasts

Vestnik Dermatologii i Venerologii, 2017
Recessive dystrophic epidermolysis bullosa (RDEB) is a severe inherited disease developing due to genetic abnormalities in the synthesis of Type VII collagen by fibroblasts.
V. I. Albanova, A. E. Karamova, V. V. Chikin, A. A. Mineyeva   +3 more
doaj   +1 more source