Results 21 to 30 of about 20,628 (210)
Collagen mRNA levels changes during colorectal cancer carcinogenesis
BMC Cancer, 2009 Background Invasive growth of epithelial cancers is a complex multi-step process which involves dissolution of the basement membrane. Type IV collagen is a major component in most basement membranes.
Tveit Kjell M +5 more
doaj +1 more source
Molecular Therapy: Methods & Clinical Development, 2022 Recessive dystrophic epidermolysis bullosa, a devastating skin fragility disease characterized by recurrent skin blistering, scarring, and a high risk of developing squamous cell carcinoma is caused by mutations in COL7A1, the gene encoding type VII ...
Marta García +12 more
doaj +1 more source
Sources of Collagen for Biomaterials in Skin Wound Healing
Bioengineering, 2019 Collagen is the most frequently used protein in the fields of biomaterials and regenerative medicine. Within the skin, collagen type I and III are the most abundant, while collagen type VII is associated with pathologies of the dermal−epidermal ...
Evan Davison-Kotler +2 more
doaj +1 more source
Cardiac valve disease: an unreported feature in Ehlers Danlos syndrome arthrocalasia type?
Italian Journal of Pediatrics, 2012 Ehlers Danlos syndrome (EDS) athrocalasia type (type VII), is characterized by joint hypermobility, skin hyperextensibility and tissue fragility. No heart involvement has been reported. Two forms have been described: type VII A and VII B.
Melis Daniela +6 more
doaj +1 more source
Immunohistochemical expression of collagen type VII antibody in the human fetal temporomandibular joint discs [PDF]
Einstein (São Paulo), 2007 Objective: To study the articular disc morphology and to analyze theimmunohistochemical expression of the type VII collagen marker inhuman fetal temporomandibular joint discs at different gestational ages.Methods: Twenty human fetal temporomandibular ...
Luís Otávio Carvalho de Morais +6 more
doaj
A Gene Gun-mediated Nonviral RNA trans-splicing Strategy for Col7a1 Repair
Molecular Therapy: Nucleic Acids, 2016 RNA trans-splicing represents an auspicious option for the correction of genetic mutations at RNA level. Mutations within COL7A1 causing strong reduction or absence of type VII collagen are associated with the severe skin blistering disease dystrophic ...
Patricia Peking +10 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
Spontaneous internal carotid artery dissection in dystrophic bullous epidermolysis - association or determinant factor? [PDF]
Romanian Journal of Neurology, 2010 Pathogenesis of spontaneous carotid artery dissection (sCAD) is still a domain of research. Classical inherited connective tissue disease, primary or systemic arteriopathies and ultrastructural alterations of the arterial wall were reported in sCAD.
Alexandra Comanescu, Monica Sabau
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Acta Dermato-Venereologica, 2018 Circulating anti-type VII collagen autoantibodies are frequently detected in patients with recessive dystrophic epidermolysis bullosa (RDEB). However, evidence supporting their pathogenic role in inducing epidermolysis bullosa acquisita (EBA) has been ...
Liliana Guerra +6 more
doaj +1 more source