Results 311 to 320 of about 300,263 (378)

Proteogenomic Characterization Reveals Subtype‐Specific Therapeutic Potential for HER2‐Low Breast Cancer

Advanced Science, EarlyView.
Multiomic profiling of HER2‐low breast cancer identifies three proteomic subtypes with distinct therapeutic strategies: endocrine, antiangiogenic, and anti‐HER2 therapies. Genomic and lactate modification landscapes are detailed, providing insights for precise management.
Shouping Xu, Keda Yu, Lei Liu, Qin Wang, Xiaohui Wu, Yihai Chen, Guozheng Li, Xin Zhang, Bo Wei, Zitong Fu, Abiyasi Nanding, Zuxianglan Zhao, Lingbing Yang, Xingda Zhang, Jianyu Wang, Wantong Sun, Yi Hao, Zhongyi Cheng, Xiaojiang Cui, Hao Wu, Da Pang   +20 more
wiley   +1 more source

First case report of <i>Shewanella indica</i> isolated from a hospitalized patient in Serbia. [PDF]

Front Med (Lausanne)
Filipić B, Žugić V, Golob M, Rambaher MH, Bošković L, Milenković MT.   +5 more
europepmc   +1 more source

Immunomodulatory Hydrogel Coating with SeNPs and Lithium Silicate Synergistically Promotes Osseointegration and Prevents Infection on Titanium Implants

Advanced Science, EarlyView.
This study introduces a multifunctional hydrogel coating (Lap‐CMCSMA/GelMA@SeNPs) that scavenges ROS, modulates immune responses, and shows strong antibacterial activity. It effectively restores the peri‐implant microenvironment. The coating exhibits excellent biocompatibility and promotes osteogenic differentiation.
Su Jiang, Baisheng Cai, Cong Ye, Kefan Wu, Kuan Liu, Pengcheng Xu, Fan Liu, Yake Liu   +7 more
wiley   +1 more source

Comparative chemical and biological study of essential oils and n-hexane extracts of Thymus vulgaris and Thymus serpyllum (Lamiaceae). [PDF]

Sci Rep
AbdelRazek MMM, Atta AM, Kandil NH, Girgis IEG, Elsayed RTO, Abdel-Latif BRM, Abdel-Halim AE, Salama SGI, Ahmed TEM, AbdelRazek MAS, Foad FH, Elsayed RMS, Aslan SHE, Badawy NIE, Farouk EA, Omran SA, Darwish KM, El-Moghazy SA.   +17 more
europepmc   +1 more source

⁠Engineering Adaptive Immunity in 3D: A Patient‐Specific Lymphoid Model Using Stromal Networks and Peripheral Blood Mononuclear Cells

Advanced Science, EarlyView.
This study presents a 3D lymphoid tissue model engineered from adipose‐derived stem cells differentiated into fibroblastic reticular cell–like networks and co‐cultured with immune cells. The engineered system successfully generates antigen‐specific antibodies and cytokine responses, providing a platform for studying adaptive immunity, vaccine efficacy,
Mei ElGindi, Shaza Karaman, Jeremy Teo
wiley   +1 more source

Perioperative changes in the microbiome during rectal cancer surgery: exploratory analysis of the National Institute for Health and Care Research (NIHR) IntAct trial. [PDF]

Br J Surg
Helliwell JA, Chilton CH, Young C, Clark EV, Wilkinson L, Fuentes Balaguer A, Bottomley D, Croft J, Corrigan N, Kirby A, Quirke P, Stocken DD, Jayne DG, Wood HM.   +13 more
europepmc   +1 more source

Quantitative analysis of calcium, A and B collagenase levels during the bone repair in rats under calvaria experimental model of bone defect

, 2013
Conrado Ingraci de Lucia
openalex   +1 more source

Magnetically‐Induced Suppression of Oxidative Stress Prevents Venous Thrombosis

Advanced Science, EarlyView.
Venous thromboembolism (VTE) remains a leading cause of cardiovascular mortality. This study demonstrates that static magnetic fields (SMF) offer a novel non‐pharmacological intervention against VTE by mitigating endothelial oxidative stress. Mechanistically, SMF elevates intracellular Ca2+, boosts ATP production, and suppresses NOX4‐mediated ROS ...
Nana Zhang, Yirong An, Shiran Tao, Shenao Qu, Minge Wu, Guantong Fang, Ziqing Chen, Weilun Song, Haoze Leng, Rongqian Wu, Yi Lyu, Xiaoli Liu, Dinghui Dong   +12 more
wiley   +1 more source

Corneal enzymatic digestion resistance in the presence of oestradiol and oestradiol plus selective tissue oestrogenic activity regulators (STEAR). [PDF]

BMJ Open Ophthalmol
Hafezi NL, Aydemir ME, Lu NJ, Torres-Netto EA, Hillen M, Koppen C.   +5 more
europepmc   +1 more source

Establishment of an ex vivo cartilage damage model by combined collagenase treatment and mechanical loading

Liru Wen, Sibylle Grad, Laura B. Creemers, Martin J. Stoddart   +3 more
openalex   +1 more source