Results 1 to 10 of about 11,362 (251)

Heterologous Expression and Characterization of Collagenases from Pseudomonas chlororaphis GP72 [PDF]

open access: yesBiology
Collagenases can specifically degrade collagen, showing a wide application prospect in food, leather, waste utilization, biotechnology, and other industries.
Dingkang Hu   +9 more
doaj   +2 more sources

Unlocking the Potential of Collagenases: Structures, Functions, and Emerging Therapeutic Horizons [PDF]

open access: yesBioDesign Research
Collagenases, a class of enzymes that are specifically responsible for collagen degradation, have garnered substantial attention because of their pivotal roles in tissue repair, remodeling, and medical interventions.
Zhen-Zhen Wang   +8 more
doaj   +2 more sources

The action of microbial collagenases in dentinal matrix degradation in root caries and potential strategies for its management: a comprehensive state-of-the-art review [PDF]

open access: yesJournal of Applied Oral Science
Conventional views associate microbial biofilm with demineralization in root caries (RC) onset, while research on their collagenases role in the breakdown of collagen matrix has been sporadically developed, primarily in vitro. Recent discoveries, however,
Cecília de Brito BARBOSA   +2 more
doaj   +2 more sources

Expression of collagenases (matrix metalloproteinase-1, -8, -13) and tissue inhibitor of metalloproteinase-3 (TIMP-3) in naturally occurring bovine cutaneous fibropapillomas

open access: yesFrontiers in Veterinary Science, 2023
Bovine cutaneous fibropapillomas are among the most common skin tumors in cattle; their etiology is associated with infection by bovine papillomavirus (BPV) types−1/-2 which are considered oncogenic.
Annunziata Corteggio   +2 more
exaly   +3 more sources

Effect of shRNA Mediated Silencing of YB-1 Protein on the Expression of Matrix Collagenases in Malignant Melanoma Cell In Vitro

open access: yesCells, 2018
Background and Objective: YB-1 is a transcription and oncogenic factor capable of binding to DNA and RNA performing versatile functions within normal and cancer cells.
Wisam Nabeel Ibrahim   +1 more
exaly   +3 more sources

Enzymatic isolation of porcine preantral follicles impairs oocyte viability and long-term in vitro growth [PDF]

open access: yesThe Journal of Reproduction and Development
The enzymatic isolation of preantral follicles (PAFs) is considered the most efficient method for retrieving a large number of intact follicles, offering significant advantages in terms of yield and processing time.
Ba Anh My LE   +10 more
doaj   +2 more sources

Bacterial collagenase harnesses collagen geometry for processive cleavage [PDF]

open access: yesNature Communications
Collagen, the major structural protein in the animal extracellular matrix, forms a triple helix that resists proteolysis and requires specialised enzymes for degradation.
Hiroya Oki   +11 more
doaj   +2 more sources

Intralesional collagenase Clostridium histolyticum vs. verapamil injections in males with Peyronie’s Disease: A prospective, matched-pair, non-blinded, randomised clinical study comparing clinical outcomes and patient satisfaction rates [PDF]

open access: yesInvestigative and Clinical Urology, 2022
Purpose: To compare clinical outcomes and patient satisfaction rates between intralesional verapamil (ILV) and collagenase Clostridium histolyticum (CCH) injections in males with Peyronie’s disease (PD). Materials and Methods: Following ethics approval,
Eric Chung, Juan Wang
doaj   +1 more source

Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC 14579. [PDF]

open access: yesPLoS ONE, 2016
Bacterial collagenases differ considerably in their structure and functions. The collagenases ColH and ColG from Clostridium histolyticum and ColA expressed by Clostridium perfringens are well-characterized collagenases that cleave triple-helical ...
Carmen M Abfalter   +11 more
doaj   +1 more source

Roles of matrix metalloproteinases in the cornea: A special focus on macular corneal dystrophy

open access: yesMedicine in Drug Discovery, 2021
Matrix metalloproteinases (MMPs) are endopeptidases that are responsible for the degradation of several components of the extracellular matrix (ECM) and some non-ECM proteins.
Saniye Gul Kaya   +5 more
doaj   +1 more source

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