Unlocking the Potential of Collagenases: Structures, Functions, and Emerging Therapeutic Horizons [PDF]
BioDesign ResearchCollagenases, a class of enzymes that are specifically responsible for collagen degradation, have garnered substantial attention because of their pivotal roles in tissue repair, remodeling, and medical interventions.
Zhen-Zhen Wang +8 more
doaj +3 more sources
The action of microbial collagenases in dentinal matrix degradation in root caries and potential strategies for its management: a comprehensive state-of-the-art review [PDF]
Journal of Applied Oral ScienceConventional views associate microbial biofilm with demineralization in root caries (RC) onset, while research on their collagenases role in the breakdown of collagen matrix has been sporadically developed, primarily in vitro. Recent discoveries, however,
Cecília de Brito BARBOSA +2 more
doaj +3 more sources
Secretion of collagenases by Saccharomyces cerevisiae for collagen degradation
Biotechnology for Biofuels and Bioproducts, 2022 Background The production and processing of animal-based products generates many collagen-rich by-products, which have received attention both for exploitation to increase their added value and to reduce their negative environmental impact.
Han Xiao +5 more
doaj +2 more sources
Heterologous Expression and Characterization of Collagenases from Pseudomonas chlororaphis GP72 [PDF]
BiologyCollagenases can specifically degrade collagen, showing a wide application prospect in food, leather, waste utilization, biotechnology, and other industries.
Dingkang Hu +9 more
doaj +2 more sources
Collagenases and gelatinases in bone healing. The focus on mandibular fractures
Current Issues in Pharmacy and Medical Sciences, 2014 Due to high amount of collagen fibres in the structure of bone, the enzymes capable of collagen digestion play a key role in bone remodelling. Matrix metalloproteinases (MMPs), prevailing extracellular endopeptideses, can digest extracellularly located ...
Kurzepa Jacek +4 more
doaj +4 more sources
Isolation of Adult Rat Cardiomyocytes Using Recombinant Collagenases
Chemical Engineering Transactions, 2018 Direct isolation of primary cells from tissues and organs allows for the maintenance of important cell characteristics and properties for in vitro studies and a plethora of biomedical applications.
S. Campora +3 more
doaj +2 more sources
An improved collagen zymography approach for evaluating the collagenases MMP-1, MMP-8, and MMP-13
BioTechniques, 2017 Collagen zymography is an SDS-PAGE–based method for detecting both the proenzyme and active forms of collagenases. Although collagen zymography is used for assessment of the matrix metalloproteinases MMP-1 and MMP-13, it can be difficult to detect these ...
Seniz Inanc, Didem Keles, Gulgun Oktay
doaj +2 more sources
Cells, 2018 Background and Objective: YB-1 is a transcription and oncogenic factor capable of binding to DNA and RNA performing versatile functions within normal and cancer cells.
Wisam Nabeel Ibrahim +1 more
exaly +3 more sources
Marine Drugs, 2017 Collagenases are the most important group of commercially-produced enzymes. However, even though biological resources are abundant in the sea, very few of these commercially popular enzymes are from marine sources, especially from marine bacteria.
Xinghao Yang +8 more
doaj +2 more sources
Enzymatic isolation of porcine preantral follicles impairs oocyte viability and long-term in vitro growth [PDF]
The Journal of Reproduction and DevelopmentThe enzymatic isolation of preantral follicles (PAFs) is considered the most efficient method for retrieving a large number of intact follicles, offering significant advantages in terms of yield and processing time.
Ba Anh My LE +10 more
doaj +2 more sources