Results 21 to 30 of about 12,280 (281)

Expression of collagenases (matrix metalloproteinase-1, -8, -13) and tissue inhibitor of metalloproteinase-3 (TIMP-3) in naturally occurring bovine cutaneous fibropapillomas

open access: yesFrontiers in Veterinary Science, 2023
Bovine cutaneous fibropapillomas are among the most common skin tumors in cattle; their etiology is associated with infection by bovine papillomavirus (BPV) types−1/-2 which are considered oncogenic.
Florentina Daraban Bocaneti   +8 more
doaj   +1 more source

Biochemical characterisation of a collagenase from Bacillus cereus strain Q1

open access: yesScientific Reports, 2021
Collagen is the most abundant protein in higher animals and as such it is a valuable source of amino acids and carbon for saprophytic bacteria. Due to its unique amino acid composition and triple-helical tertiary structure it can however only be cleaved ...
Isabel J. Hoppe   +2 more
doaj   +1 more source

Neural Crest-Derived Chondrocytes Isolation for Tissue Engineering in Regenerative Medicine

open access: yesCells, 2020
Chondrocyte transplantation has been successfully tested and proposed as a clinical procedure aiming to repair articular cartilage defects. However, the isolation of chondrocytes and the optimization of the enzymatic digestion process, as well as their ...
Monica Salamone   +7 more
doaj   +1 more source

Matrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions [PDF]

open access: yesVojnosanitetski Pregled, 2008
Background/Aim. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive ...
Andonovska Biljana   +2 more
doaj   +1 more source

Taxonomic and Enzymatic Characterization of Flocculibacter collagenilyticus gen. nov., sp. nov., a Novel Gammaproteobacterium With High Collagenase Production

open access: yesFrontiers in Microbiology, 2021
Collagens from marine animals are an important component of marine organic nitrogen. Collagenase-producing bacteria and their collagenases play important roles in collagen degradation and organic nitrogen recycling in the ocean.
Jian Li   +15 more
doaj   +1 more source

Discovery and Characterization of Synthesized and FDA-Approved Inhibitors of Clostridial and Bacillary Collagenases

open access: yes, 2022
In view of the worldwide antimicrobial resistance (AMR) threat, new bacterial targets and anti-infective agents are needed. Since important roles in bacterial pathogenesis have been demonstrated for the collagenase H and G (ColH and ColG) from ...
Constantin Blöchl (12123532)   +12 more
core   +2 more sources

Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake

open access: yesCell Reports, 2017
Physiologic turnover of interstitial collagen is mediated by a sequential pathway in which collagen is fragmented by pericellular collagenases, endocytosed by collagen receptors, and routed to lysosomes for degradation by cathepsins.
Daniel Hargbøl Madsen   +9 more
doaj   +1 more source

Collagen V Is a Potential Substrate for Clostridial Collagenase G in Pancreatic Islet Isolation

open access: yesJournal of Diabetes Research, 2016
The clostridial collagenases, H and G, play key roles in pancreatic islet isolation. Collagenases digest the peptide bond between Yaa and the subsequent Gly in Gly-Xaa-Yaa repeats.
Hiroki Shima   +7 more
doaj   +1 more source

In Vitro Study of a Novel Vibrio alginolyticus-Based Collagenase for Future Medical Application

open access: yesCells, 2023
Mesenchymal stem cells extracted from adipose tissue are particularly promising given the ease of harvest by standard liposuction and reduced donor site morbidity.
Lindsey Alejandra Quintero Sierra   +12 more
doaj   +1 more source

Cloning and sequencing of mouse collagenase cDNA. Divergence of mouse and rat collagenases from the other mammalian collagenases.

open access: yes, 1992
Mouse collagenase cDNA was cloned and sequenced. The deduced amino acid sequence was compared to those of the other mammalian collagenases and related matrix metalloproteinases.
Rousseau, Guy   +6 more
core   +1 more source

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