Results 11 to 20 of about 12,280 (281)
Endogenous Collagenases Regulate Osteoclast Fusion
Biomolecules, 2020 The precise regulation of osteoclast differentiation and function is crucial for the maintenance of healthy bone. Despite several reports of collagenase expression in bone tissues, the precise isoform expression as well as the role in osteoclasts are ...
Hyo Jeong Kim, Youngkyun Lee
doaj +2 more sources
Chemical Engineering Transactions, 2012 One of the main success practices in cell therapy is the transplantation of allogeneic pancreatic islets cells in patients with type 1 diabetes. However, at the moment less than 50 % of procedures are successfully completed; this is because the procedure
M. Salamone +5 more
doaj +2 more sources
Фармация и фармакология (Пятигорск), 2019 The aim of this study was to assess the coverage of studies of collagenolytic enzymes (collagenases) in the sphere of their use in wounds and scars treatment, the resource of their production and the range of collagenase products to identify the areas ...
A. V. Mayorova +3 more
doaj +4 more sources
Collagenases and Collagen Degradation.
Journal of Investigative Dermatology, 1982 Degradation of interstitial collagens probably takes place through different enzymatic mechanisms than degradation of basement membrane and pericellular collagens. Interstitial collagens are resorbed under pathological and physiological conditions by collagenases which function extracellularly and cleave polypeptide chains in the collagen triple helix ...
Krane, Stephen M.
openaire +3 more sources
The role of collagenase in emphysema [PDF]
Respiratory Research, 2001 The extracellular matrix is essential for the integrity of the lung and when disrupted can lead to the architectural changes seen in emphysema. The etiology of emphysema is believed to be due to an imbalance in the proteases and antiproteases within the ...
D'Armiento Jeanine, Foronjy Robert
doaj +4 more sources
Tissue Dissociation and Primary Cells Isolation Using Recombinant Collagenases Class I and II
Chemical Engineering Transactions, 2014 Collagenases class I (Col G) and class II (Col H) currently available for tissue dissociation are produced from Clostridium histolyticum (human pathogen) strains.
M. Salamone +4 more
doaj +2 more sources
Intralesional collagenase Clostridium histolyticum vs. verapamil injections in males with Peyronie’s Disease: A prospective, matched-pair, non-blinded, randomised clinical study comparing clinical outcomes and patient satisfaction rates [PDF]
Investigative and Clinical Urology, 2022 Purpose: To compare clinical outcomes and patient satisfaction rates between intralesional verapamil (ILV) and collagenase Clostridium histolyticum (CCH) injections in males with Peyronie’s disease (PD). Materials and Methods: Following ethics approval,
Eric Chung, Juan Wang
doaj +1 more source
Cloning, Purification and Characterization of the Collagenase ColA Expressed by Bacillus cereus ATCC 14579. [PDF]
PLoS ONE, 2016 Bacterial collagenases differ considerably in their structure and functions. The collagenases ColH and ColG from Clostridium histolyticum and ColA expressed by Clostridium perfringens are well-characterized collagenases that cleave triple-helical ...
Carmen M Abfalter +11 more
doaj +1 more source
Roles of matrix metalloproteinases in the cornea: A special focus on macular corneal dystrophy
Medicine in Drug Discovery, 2021 Matrix metalloproteinases (MMPs) are endopeptidases that are responsible for the degradation of several components of the extracellular matrix (ECM) and some non-ECM proteins.
Saniye Gul Kaya +5 more
doaj +1 more source
Biomolecules, 2020 The diagnostic accuracy of point-of-care (PoC) applications may be compromised in individuals with additional inflammatory conditions. This cross-sectional study examined the performance of a commercial oral rinse active matrix metalloproteinase-8 (aMMP ...
Jaana Rautava +6 more
doaj +1 more source