Results 11 to 20 of about 11,362 (251)
The role of collagenase in emphysema [PDF]
Respiratory Research, 2001 The extracellular matrix is essential for the integrity of the lung and when disrupted can lead to the architectural changes seen in emphysema. The etiology of emphysema is believed to be due to an imbalance in the proteases and antiproteases within the ...
D'Armiento Jeanine, Foronjy Robert
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Secretion of collagenases by Saccharomyces cerevisiae for collagen degradation
Biotechnology for Biofuels and Bioproducts, 2022 Background The production and processing of animal-based products generates many collagen-rich by-products, which have received attention both for exploitation to increase their added value and to reduce their negative environmental impact.
Han Xiao +5 more
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Biomolecules, 2020 The diagnostic accuracy of point-of-care (PoC) applications may be compromised in individuals with additional inflammatory conditions. This cross-sectional study examined the performance of a commercial oral rinse active matrix metalloproteinase-8 (aMMP ...
Jaana Rautava +6 more
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Biochemical characterisation of a collagenase from Bacillus cereus strain Q1
Scientific Reports, 2021 Collagen is the most abundant protein in higher animals and as such it is a valuable source of amino acids and carbon for saprophytic bacteria. Due to its unique amino acid composition and triple-helical tertiary structure it can however only be cleaved ...
Isabel J. Hoppe +2 more
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Neural Crest-Derived Chondrocytes Isolation for Tissue Engineering in Regenerative Medicine
Cells, 2020 Chondrocyte transplantation has been successfully tested and proposed as a clinical procedure aiming to repair articular cartilage defects. However, the isolation of chondrocytes and the optimization of the enzymatic digestion process, as well as their ...
Monica Salamone +7 more
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Matrix metalloproteinases (MMP-1, -8, -13) in chronic periapical lesions [PDF]
Vojnosanitetski Pregled, 2008 Background/Aim. Matrix metalloproteinases (MMPs) are proteolytic enzymes capable of degrading almost all extracellular matrix and basement membrane components in many destructive pathological processes, such as chronic inflammation and bone-destructive ...
Andonovska Biljana +2 more
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Frontiers in Microbiology, 2021 Collagens from marine animals are an important component of marine organic nitrogen. Collagenase-producing bacteria and their collagenases play important roles in collagen degradation and organic nitrogen recycling in the ocean.
Jian Li +15 more
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Endogenous Collagenases Regulate Osteoclast Fusion
Biomolecules, 2020 The precise regulation of osteoclast differentiation and function is crucial for the maintenance of healthy bone. Despite several reports of collagenase expression in bone tissues, the precise isoform expression as well as the role in osteoclasts are ...
Hyo Jeong Kim, Youngkyun Lee
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Collagenases and gelatinases in bone healing. The focus on mandibular fractures
Current Issues in Pharmacy and Medical Sciences, 2014 Due to high amount of collagen fibres in the structure of bone, the enzymes capable of collagen digestion play a key role in bone remodelling. Matrix metalloproteinases (MMPs), prevailing extracellular endopeptideses, can digest extracellularly located ...
Kurzepa Jacek +4 more
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Cell Reports, 2017 Physiologic turnover of interstitial collagen is mediated by a sequential pathway in which collagen is fragmented by pericellular collagenases, endocytosed by collagen receptors, and routed to lysosomes for degradation by cathepsins.
Daniel Hargbøl Madsen +9 more
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