Results 61 to 70 of about 6,990 (303)

Time‐Controlled Refrigerated Stem Cell Therapy Mitigates Scleroderma Fibrosis via Modulation of Mitochondrial Autophagy and Gut Metabolism

Advanced Science, EarlyView.
This study established an RT‐MSCs‐based therapeutic approach for scleroderma in mice. RT‐MSCs attenuated fibrosis by regulating mitochondrial autophagy and restored gut microbiota homeostasis. Metabolomic analyses confirmed recovery of key metabolites, and RT‐MSCs demonstrated favorable lesion targeting and safety profiles.
Xue Xia, Chenfei Kong, Xiaoming Zhao, Naixu Shi, Jinlan Jiang, Ping Li   +5 more
wiley   +1 more source

Use of budesonide in the treatment of microscopic colitis

The Saudi Journal of Gastroenterology, 2010
Collagenous colitis and lymphocytic colitis, the two types of microscopic colitis, cause watery diarrhea. Budesonide, a glucocorticoid medication with limited systemic availability, is commonly used to treat these illnesses.
Tangri Vikram, Chande Nilesh
doaj  

Pediatric Gastrointestinal Endoscopy: European Society of Pediatric Gastroenterology Hepatology and Nutrition (ESPGHAN) and European Society of Gastrointestinal Endoscopy (ESGE) Guidelines [PDF]

, 2017
: This Guideline refers to infants, children and adolescents aged 0–18 years. The areas covered include: indications for diagnostic and therapeutic esophagogastroduodenoscopy and ileo-colonoscopy; endoscopy for foreign body ingestion; corrosive ingestion
Aabakken, L. (Lars), Amil-Dias, J. (Jorge), Benninga, M.A. (Marc), Brownstone, E. (Eva), Dall’Oglio, L. (Luigi), Dolak, W. (Werner), Dumonceau, J.M., Everett, S. (Simon), Furlano, R. (Raoul), Gerner, P. (Patrick), Hassan, C. (Cesare), Hlava, Š. (Štěpán), Huber, W.D. (Wolf Dietrich), IJsselstijn, H. (Hanneke), Keil, R. (Radan), Landi, R. (Rosario), Orel, R. (Rok), Romano, C. (Claudio), Spaander, M.C.W. (Manon), Tabbers, M.M., Tavares, M. (Marta), Thomson, M. (Mike), Tringali, A. (A.), Tzvinikos, C. (Christos), Vandenplas, Y. (Yvan), Vecsei, A. (Andreas), Viala, J. (Jérôme), Zambelli, A. (Alessandro)   +27 more
core   +2 more sources

Mechanostimulatory Cues Determine Intestinal Fibroblast Fate and Profibrotic Remodeling in a Physiodynamic Human Gut‐on‐a‐Chip

Advanced Science, EarlyView.
A healthy gut barrier shields underlying fibroblasts from luminal shear forces, illustrating that “good fences make good neighbors.” Barrier damage exposes fibroblasts to shear stress, inducing cell death and the emergence of stress‐adapted, profibrotic fibroblasts. Sustained shear exposure promotes the formation of stiff aggregates of mechanoadapative
Soyoun Min, Nam Than, Yong Cheol Shin, Elif G. Ertugral, Chandrasekhar R. Kothapalli, Olumuyiwa Awoniyi, Hyun Jung Kim   +6 more
wiley   +1 more source

Europe's contribution to the evaluation of the use of systemic antimicrobials in the treatment of periodontitis

Periodontology 2000, EarlyView., 2023
Abstract This narrative review celebrates Europe's contribution to the current knowledge on systemically administered antimicrobials in periodontal treatment. Periodontitis is the most frequent chronic noncommunicable human disease. It is caused by dysbiotic bacterial biofilms and is commonly treated with subgingival instrumentation.
David Herrera, Arie Jan van Winkelhoff, Paula Matesanz, Katalina Lauwens, Wim Teughels   +4 more
wiley   +1 more source

Collagenous Colitis: Histologic Progression, Extraintestinal Features and Lack of Response to 5-ASA - A Case Report

Canadian Journal of Gastroenterology, 1990
Collagenous colitis is a clinicopathologic syndrome which presents as chronic, watery, nonbloody diarrhea. Colonic biopsies characteristically show a thick subepithelial collagen band.
Franzjosef Schweiger
doaj   +1 more source

Gut Lactate Boosts Ruminococcus via Histone Lactylation to Mediate Time‐Restricted Feeding Protection in Crohn's Disease

Advanced Science, EarlyView.
TRF enriches Ruminococcus, a bacterial genus producing SCFAs, and activates the epithelial HIF‐1α signaling pathway. This mechanism protects the colonic mucosa from inflammatory insults in colitis models. Mechanistically, gut lactate production during starvation and refeeding mediates H4K12la, which increases SLC9A3 expression and creates an acidic gut
Linwen Huang, Huishi Tan, Senhui Weng, Yuntao Liu, Lingxu Song, Shaoyu Cheng, Zelong Lin, Jiawei Chen, Fei Tan, Jun Wang, Jinke Huang, Linkun Cai, Jiwei Chai, Cailing Zhong, Yanqiang Shi, Wendi Zhang, Haiyan Zhang, Chongyang Huang   +17 more
wiley   +1 more source

Perinuclear Antineutrophil Cytoplasmic Antibodies in Collagenous or Lymphocytic Colitis with or without Celiac Disease

Canadian Journal of Gastroenterology, 1997
Microscopic forms of colitis, including lymphocytic and collagenous colitis, have been observed in both those with and without celiac disease.
Hugh James Freeman
doaj   +1 more source

Microscopic colitis - review [PDF]

, 2008
Neðst á síðunni er hægt að nálgast greinina í heild sinni með því að smella á hlekkinn View/OpenMicroscopic colitis (MC) is an encompassing term for two diseases; collagenous colitis and lymphocytic colitis.
Jón Gunnlaugur Jónasson, Kjartan B. Örvar, Sigurbjörn Birgisson, Ólafur Á. Sveinsson   +3 more
core  

Autoimmune enteropathy with a CD8+ CD7-T-cell small bowel intraepithelial lymphocytosis: case report and literature review [PDF]

, 2011
Background Adult onset autoimmune enteropathy (AIE) is a rare condition characterized by diarrhea refractory to dietary therapy diagnosed in patients with evidence of autoimmune conditions.
Eun Y Lee, H David Vargas, Razvan Arsenescu, Shrinivas Bishu, Violeta Arsenescu, Willem JS de Villiers   +5 more
core   +4 more sources