Altered collecting duct adenylyl cyclase content in collecting duct endothelin-1 knockout mice [PDF]
BMC Nephrology, 2007 Background Endothelin-1 (ET-1) inhibition of vasopressin (AVP)-stimulated water reabsorption by the inner medullary collecting duct (IMCD) is associated with reduced cAMP accumulation.
Kohan Donald E +2 more
doaj +5 more sources
Collecting duct NCOR1 controls blood pressure by regulating mineralocorticoid receptor [PDF]
Journal of Advanced ResearchIntroduction: Nuclear receptor corepressor 1(NCOR1) is reported to play crucial roles in cardiovascular diseases, but its function in the kidney has remained obscure. Objective: We aim to elucidate the role of collecting duct NCOR1 in blood pressure (BP)
Ke Sun +8 more
doaj +4 more sources
Claudins in the Renal Collecting Duct [PDF]
International Journal of Molecular Sciences, 2019 The renal collecting duct fine-tunes urinary composition, and thereby, coordinates key physiological processes, such as volume/blood pressure regulation, electrolyte-free water reabsorption, and acid-base homeostasis. The collecting duct epithelium is comprised of a tight epithelial barrier resulting in a strict separation of intraluminal urine and the
Janna Leiz, Kai M. Schmidt-Ott
openaire +6 more sources
Differentiated mouse kidney tubuloids as a novel in vitro model to study collecting duct physiology [PDF]
Frontiers in Cell and Developmental Biology, 2023 Kidney tubuloids are cell models that are derived from human or mouse renal epithelial cells and show high similarities with their in vivo counterparts. Tubuloids grow polarized in 3D, allow for long-term expansion, and represent multiple segments of the
C. J. A. Olde Hanhof +15 more
doaj +2 more sources
Modus operandi of ClC-K2 Cl− Channel in the Collecting Duct Intercalated Cells [PDF]
Biomolecules, 2023 The renal collecting duct is known to play a critical role in many physiological processes, including systemic water–electrolyte homeostasis, acid–base balance, and the salt sensitivity of blood pressure.
Anna Stavniichuk +5 more
doaj +2 more sources
Metastatic collecting duct carcinoma of the kidney treated with sunitinib [PDF]
World Journal of Surgical Oncology, 2011 Collecting duct carcinoma (CDC) of the kidney is a rare and aggressive malignant tumor arising from the distal collecting tubules which has been shown to have a poor response to several kinds of systemic therapy.
M'rabti Hind +5 more
doaj +5 more sources
A complete response to Pembrolizumab for metastatic collecting duct carcinoma of the kidney [PDF]
Urology Case ReportsCollecting duct carcinoma, also known as Bellini duct cancer, is a rare subtype of renal cell carcinoma with a poor prognosis in the metastatic setting.
Satoki Abe +5 more
doaj +2 more sources
Collecting duct carcinoma associated with oncocytoma [PDF]
International Brazilian Journal of Urology, 2005 Collecting duct carcinoma (CDC) is a rare, highly aggressive malignant neoplasm that arises from the collecting duct epithelium of the kidney. CDC was reported to coexist with renal cell and transitional cell carcinomas.
George M. Yousef +3 more
doaj +5 more sources
A rare case of collecting duct renal cell carcinoma [PDF]
Urology Case ReportsCollecting duct carcinoma is an exceptionally rare and aggressive form of renal cell carcinoma (RCC), representing between 0.4 and 1.8% of RCC cases. The most commonly affected demographic are young African-American males. Here, we present a rare case of
Vance Gentry +3 more
doaj +2 more sources
Clear cell renal cell carcinoma with collecting duct carcinoma transformation: a case report and review of the literature [PDF]
BMC UrologyCollecting duct carcinoma (CDC), a rare and aggressive renal malignancy originating from the medullary collecting ducts, often presents with nonspecific symptoms and rapid metastatic progression, yielding a dismal prognosis. The occurrence of a composite
Mingwei Liang +4 more
doaj +2 more sources