Results 41 to 50 of about 30,417 (250)

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Collecting duct carcinoma of kidney: Masquerading as genitourinary tuberculosis - Lessons learnt

Urology Case Reports, 2020
We present a case of Collecting duct of Bellini carcinoma (CDC) which was masquerading as Genitourinary Tuberculosis/chronic granulomatous disease in a 43 year old women, who presented with complaints of low grade fever, loss of appetite, left loin pain ...
Mathisekaran T, Deepak Raghavan, Ranjanee Muthu, Vikram Prabhakar, Sanjay Prakash   +4 more
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Collecting Duct Renal Cell Carcinoma Found to Involve the Collecting System During Partial Nephrectomy: A Case Report

Journal of Kidney Cancer and VHL, 2015
Collecting duct carcinoma (CDC) is a rare and aggressive form of renal cell carcinoma (RCC) arising from the principal cells of the collecting duct.  One third of cases present with metastatic disease, but many present in a manner similar to conventional
Andrew C Harbin, Brett A Styskel, Viren Patel, He Wang, Daniel D Eun   +4 more
doaj   +1 more source

Rhabdoid collecting duct carcinoma with lymphangitic carcinomatosis causing acute lethal chylopericardium

Respiratory Medicine Case Reports, 2020
Collecting duct carcinoma is a rare neoplasm of the kidney, accounting for only 1–2% of renal tumors. These tumors arise from the principal cells of the renal collecting ducts of Bellini.
Juan Carlos Alvarez Moreno, Michael Pagacz, Odille Mejia, Kei-Shing Oh, Ana Maria Medina   +4 more
doaj   +1 more source

Using cell‐free RNA to identify B‐ and T‐cell clonality for diagnosis and monitoring of B‐ and T‐cell neoplasms

FEBS Open Bio, EarlyView.
Using peripheral blood for determining B‐cell or T‐cell clonality is more reliable when we use cell‐free RNA (cfRNA) because cells release blood significantly more RNA than DNA. Next‐generation sequencing (NGS) of cfRNA allows us to evaluate fragment cfRNA and evaluate clonality reliably without the need for prior determination of the specific dominant
Adam Albitar, Sally Agersborg, Ahmed Charifa, Pooja Phull, Noa Biran, David Vesole, Harsh Parmar, Andrew Pecora, Andrew Ip, Andre Goy, David Siegel, Maher Albitar   +11 more
wiley   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

COLLECTING DUCT CARCINOMA OF THE KIDNEY: REPORT OF TWO CASES

Urology Research and Practice, 2019
Introduction: Collecting duct carcinoma is a rare neoplasm of the kidney. It is highly aggressive and life expectancy of patients is usually very poor. For the majority of patients, surgical treatment will not result in cure.
Tahsin TURUNÇ, Filiz Bulat, Tulga EĞİLMEZ, Sezgin Güvel, Hakan ÖZKARDEŞ   +4 more
doaj   +2 more sources

Anorectal Dysfunction in Systemic Sclerosis: Clinical Phenotypes and Functional Patterns

Arthritis Care &Research, EarlyView.
Objective The aim of this study was to characterize specific physiologic defects in anorectal dysfunction in systemic sclerosis (SSc) using anorectal manometry (ARM), evaluate associations with gastrointestinal (GI) and extraintestinal clinical phenotypes, and explore potential serologic markers for risk stratification.
Timothy Kaniecki, Alireza Amindarolzarbi, Tsion Abdi, John Clarke, Michael Hughes, Ami A. Shah, Zsuzsanna H. McMahan   +6 more
wiley   +1 more source

Viewing Cortical Collecting Duct Function Through Phenotype-guided Single-Tubule Proteomics

Function, 2020
The revolution of the omics technologies has enabled profiling of the molecules of any sample. However, the heterogeneity of the kidney with highly specialized nephron segments like the cortical collecting duct (CCD) poses a challenge regarding ...
Nina Himmerkus, Samuel L Svendsen, Catarina Quintanova, Markus Bleich, Otto Von Schwerdtner, Thomas Benzing, Paul A Welling, Jens Leipziger, Markus M Rinschen   +8 more
doaj   +1 more source