Results 51 to 60 of about 599,745 (242)

Collecting duct carcinoma of kidney: Masquerading as genitourinary tuberculosis - Lessons learnt

open access: yesUrology Case Reports, 2020
We present a case of Collecting duct of Bellini carcinoma (CDC) which was masquerading as Genitourinary Tuberculosis/chronic granulomatous disease in a 43 year old women, who presented with complaints of low grade fever, loss of appetite, left loin pain ...
Mathisekaran T   +4 more
doaj   +1 more source

Patent arterial duct occlusion with two amplatzer duct occluder devices [PDF]

open access: yes, 2011
It is accepted practice to close large patent arterial ducts (PDA) with Amplatzer duct occluder devices, with extremely low rates of residual PDA. This article reports a child who required device closure of PDA with two Amplatzer PDA devices on two ...
DeGiovanni, Joseph V., Grech, Victor E.
core  

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Collecting Duct Renal Cell Carcinoma Found to Involve the Collecting System During Partial Nephrectomy: A Case Report

open access: yesJournal of Kidney Cancer and VHL, 2015
Collecting duct carcinoma (CDC) is a rare and aggressive form of renal cell carcinoma (RCC) arising from the principal cells of the collecting duct.  One third of cases present with metastatic disease, but many present in a manner similar to conventional
Andrew C Harbin   +4 more
doaj   +1 more source

Rhabdoid collecting duct carcinoma with lymphangitic carcinomatosis causing acute lethal chylopericardium

open access: yesRespiratory Medicine Case Reports, 2020
Collecting duct carcinoma is a rare neoplasm of the kidney, accounting for only 1–2% of renal tumors. These tumors arise from the principal cells of the renal collecting ducts of Bellini.
Juan Carlos Alvarez Moreno   +4 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Organization of collecting duct intercalated cells [PDF]

open access: yes, 1990
In recent years, the phenomenology of collecting duct HCO3 transport has been well described. It is clear that the cortical collecting duct (CCD) of both the rat and rabbit secretes HCO3 if the animal has been alkali-loaded, whereas this nephron segment ...
Schuster, Victor L.
core   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

COLLECTING DUCT CARCINOMA OF THE KIDNEY: REPORT OF TWO CASES

open access: yesUrology Research and Practice, 2019
Introduction: Collecting duct carcinoma is a rare neoplasm of the kidney. It is highly aggressive and life expectancy of patients is usually very poor. For the majority of patients, surgical treatment will not result in cure.
Tahsin TURUNÇ   +4 more
doaj   +2 more sources

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

open access: yesFEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang   +10 more
wiley   +1 more source

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