Results 51 to 60 of about 30,417 (250)
Coordinated Architectural and Chemical Reinforcement in the Crushing Mandible of a Soldier Termite
The crushing mandible of a soldier termite withstands substantial biting loads despite lacking mineral. Its cuticle is partitioned: convex teeth pair hardness and zinc enrichment with aligned chitin fibers for contact durability, while stiffer concave regions between teeth carry bending loads.
Andrew Tran Nguyen +16 more
wiley +1 more source
Sarcomatoid Collecting Duct Carcinoma
Abstract Background. —Collecting duct carcinoma has recently been recognized as a distinct entity among renal cell carcinomas and shows aggressive clinical behavior. Design.
openaire +2 more sources
Tomographic Printing in a Chip: A Versatile Platform for Biomimetic 3D Organ‐on‐Chip
A novel light‐based bioprinting approach, TVAM‐in‐a‐chip, enables rapid, contactless fabrication of biomimetic 3D organ‐on‐chip devices directly within preassembled microfluidic platforms. This strategy supports diverse materials, including cell‐laden resins, and eliminates post‐assembly steps.
Riccardo Rizzo +3 more
wiley +1 more source
A porous parylene‐coated electrode loaded with dexamethasone was developed to reduce inflammation after cochlear implantation. In guinea pigs, the device provided sustained drug release, maintained biocompatibility, improved auditory brainstem response thresholds, and reduced inflammatory cell infiltration and TNF‐α expression.
Chi‐Chieh Chang +11 more
wiley +1 more source
Background and purpose: Collecting duct carcinomas of the kidney are a rare malignant tumor accounting for <1% of renal malignancies. It is associated with aggressive nature and more than 50% of patients have metastatic disease at the time of initial ...
黄英杰 +4 more
doaj
A coordinated progression of progenitor cell states initiates urinary tract development
Nephric duct (ND)-derived ureteric buds (UB) form the kidney collecting duct system, while ureteric tips promote nephron formation. Here the authors use single-cell RNA-seq and introduce Cluster RNA-seq to identify four progenitor populations in ...
Oraly Sanchez-Ferras +8 more
doaj +1 more source
The role of the collecting duct in urinary concentration
In summary, the three major segments of the collecting duct subserve three different functions in the urinary concentrating mechanism. The main function of the cortical collecting tubule is to raise the fractional solute contribution and absolute concentration of urea in fluid that it delivers to the outer medullary collecting duct. The function of the
openaire +2 more sources
Chloride secretion by renal collecting ducts [PDF]
Renal collecting ducts maintain NaCl homeostasis by fine-tuning urinary excretion to balance dietary salt intake. This review focuses on recent studies on transcellular Cl secretion by collecting ducts, its regulation and its role in cyst growth in autosomal dominant polycystic kidney disease (ADPKD).Lumens of nonperfused rat medullary collecting ducts
Madhumitha, Rajagopal, Darren P, Wallace
openaire +2 more sources
A GSH‐responsive AIE nanoplatform (TSH NPs) with RGD‐mediated tumor targeting co‐delivers a photosensitizer (TPA) and HCPT for extrahepatic cholangiocarcinoma. The system synergistically enhances PDT and chemotherapy by suppressing HIF‐1α/VEGF‐driven hypoxic adaptation, effectively overcoming PDT resistance.
Yong Qu +19 more
wiley +1 more source
Regulation of aquaporin-2 in the kidney: A molecular mechanism of body-water homeostasis
The kidneys play a key role in the homeostasis of body water and electrolyte balance. Aquaporin-2 (AQP2) is the vasopressin-regulated water-channel protein expressed at the connecting tubule and collecting duct, and plays a key role in urine ...
Tae-Hwan Kwon +2 more
doaj +1 more source

