A case of an advanced renal collecting duct carcinoma in which initial therapeutic effect was achieved with pembrolizumab plus axitinib [PDF]
Introduction Renal collecting duct carcinoma is often found in advanced cancers and has a poor prognosis. Here, we present the case of symptomatic metastatic collecting duct carcinoma in which we observed an initial therapeutic effect of immune ...
Yuichiro Atagi +9 more
doaj +2 more sources
Full of twists and turns: Collecting duct carcinoma presenting as persistent cough [PDF]
We report a case of collecting duct carcinoma (CDC) in a 60-year-old man who presented with persistent cough, low back pain, and weight loss. Contrast-enhanced CT of chest and abdomen revealed a mass in the medulla of the middle and upper parts of the ...
Xueying Li +3 more
doaj +2 more sources
Thick Ascending Limb Specific Inactivation of Myh9 and Myh10 Myosin Motors Results in Progressive Kidney Disease and Drives Sex-specific Cellular Adaptation in the Distal Nephron and Collecting Duct [PDF]
Our previous work established a role for myosin motor proteins MYH9 and MYH10 in trafficking of thick ascending limb (TAL) cargoes uromodulin and Na+-K+-2Cl- cotransporter NKCC2.
Karla L Otterpohl +13 more
doaj +2 more sources
FAK–Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique [PDF]
Summary This report describes a hierarchical screening technique for identification of pathways that control the morphogenesis of the renal collecting duct system. The multi-step screen involves a first round using a 2-dimensional, cell-line-based scrape-
Guangping Tai +2 more
doaj +4 more sources
Bellini Duct Carcinoma: A Rare Entity [PDF]
Bellini duct carcinoma of kidney derives from collecting duct and is associated with an aggressive course and extremely poor prognosis. Here, we report an interesting case of Collecting Duct Carcinoma (CDC) with Inferior Vena Cava (IVC) thrombus and ...
Amit Kumar Mishra +4 more
doaj +1 more source
Collecting Duct Carcinoma and Endemic Nephropathy – Case Reports and Literature Review
Although collecting duct carcinoma is a subtype of renal cell carcinoma, several studies implicate association with urothelial carcinoma. The coexistence of collecting duct carcinoma and another renal neoplasm is rare.
Matej Knežević +7 more
doaj +1 more source
Collecting Duct Carcinoma: A Rare Entity
Collecting duct carcinoma is a rare and highly aggressive subtype of renal cell carcinoma. The incidence rate is less than 1-2% of all renal tumors and usually, affect middle-aged adult, commonly in men.
Ferdinant Martinus Djawa +1 more
doaj +1 more source
Introduction Immunotherapy‐based combinations have become the standard first‐line therapy for metastatic renal cell carcinoma. However, combined immunotherapy for renal collecting duct carcinoma had been reported, but its therapeutic efficacy had been ...
Shinji Tamada +8 more
doaj +1 more source
Collecting duct carcinoma, also known as Bellini duct carcinoma (BDC) is a rare type of renal tumor, arising from the distal collecting ducts. The prognosis of this disease is extremely poor due to its rapid progression with widespread metastasis.
Amine EL. Houmaidi +5 more
doaj +1 more source
Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary +2 more
core +3 more sources

