Results 11 to 20 of about 105,733 (289)

A case of an advanced renal collecting duct carcinoma in which initial therapeutic effect was achieved with pembrolizumab plus axitinib [PDF]

open access: yesIJU Case Reports
Introduction Renal collecting duct carcinoma is often found in advanced cancers and has a poor prognosis. Here, we present the case of symptomatic metastatic collecting duct carcinoma in which we observed an initial therapeutic effect of immune ...
Yuichiro Atagi   +9 more
doaj   +2 more sources

Full of twists and turns: Collecting duct carcinoma presenting as persistent cough [PDF]

open access: yesUrology Case Reports, 2022
We report a case of collecting duct carcinoma (CDC) in a 60-year-old man who presented with persistent cough, low back pain, and weight loss. Contrast-enhanced CT of chest and abdomen revealed a mass in the medulla of the middle and upper parts of the ...
Xueying Li   +3 more
doaj   +2 more sources

Thick Ascending Limb Specific Inactivation of Myh9 and Myh10 Myosin Motors Results in Progressive Kidney Disease and Drives Sex-specific Cellular Adaptation in the Distal Nephron and Collecting Duct [PDF]

open access: yesFunction
Our previous work established a role for myosin motor proteins MYH9 and MYH10 in trafficking of thick ascending limb (TAL) cargoes uromodulin and Na+-K+-2Cl- cotransporter NKCC2.
Karla L Otterpohl   +13 more
doaj   +2 more sources

FAK–Src signalling is important to renal collecting duct morphogenesis: discovery using a hierarchical screening technique [PDF]

open access: yesBiology Open, 2013
Summary This report describes a hierarchical screening technique for identification of pathways that control the morphogenesis of the renal collecting duct system. The multi-step screen involves a first round using a 2-dimensional, cell-line-based scrape-
Guangping Tai   +2 more
doaj   +4 more sources

Bellini Duct Carcinoma: A Rare Entity [PDF]

open access: yesJournal of Clinical and Diagnostic Research, 2016
Bellini duct carcinoma of kidney derives from collecting duct and is associated with an aggressive course and extremely poor prognosis. Here, we report an interesting case of Collecting Duct Carcinoma (CDC) with Inferior Vena Cava (IVC) thrombus and ...
Amit Kumar Mishra   +4 more
doaj   +1 more source

Collecting Duct Carcinoma and Endemic Nephropathy – Case Reports and Literature Review

open access: yesActa Clinica Croatica, 2020
Although collecting duct carcinoma is a subtype of renal cell carcinoma, several studies implicate association with urothelial carcinoma. The coexistence of collecting duct carcinoma and another renal neoplasm is rare.
Matej Knežević   +7 more
doaj   +1 more source

Collecting Duct Carcinoma: A Rare Entity

open access: yesQanun Medika: Jurnal Kedokteran Fakultas Kedokteran Universitas Muhammadiyah Surabaya, 2020
Collecting duct carcinoma is a rare and highly aggressive subtype of renal cell carcinoma. The incidence rate is less than 1-2% of all renal tumors and usually, affect middle-aged adult, commonly in men.
Ferdinant Martinus Djawa   +1 more
doaj   +1 more source

Efficacy of combination therapy with pembrolizumab and axitinib for metastatic renal collecting duct cell carcinoma: A report on two cases

open access: yesIJU Case Reports, 2022
Introduction Immunotherapy‐based combinations have become the standard first‐line therapy for metastatic renal cell carcinoma. However, combined immunotherapy for renal collecting duct carcinoma had been reported, but its therapeutic efficacy had been ...
Shinji Tamada   +8 more
doaj   +1 more source

A huge collecting duct carcinoma of the kidney in an elderly woman: Diagnosis and managment challenge (uncommon condition)

open access: yesUrology Case Reports, 2020
Collecting duct carcinoma, also known as Bellini duct carcinoma (BDC) is a rare type of renal tumor, arising from the distal collecting ducts. The prognosis of this disease is extremely poor due to its rapid progression with widespread metastasis.
Amine EL. Houmaidi   +5 more
doaj   +1 more source

Functional expression of TRPV4 channels in human collecting duct cells: implications for secondary hypertension in diabetic nephropathy [PDF]

open access: yes, 2012
Background. The Vanilloid subfamily of transient receptor potential (TRPV) ion channels has been widely implicated in detecting osmotic and mechanical stress.
Bland, Rosemary   +2 more
core   +3 more sources

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