Results 111 to 120 of about 5,280,218 (348)

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Women's Action Collective Abortion Task Force counterprotest notice

open access: yes, 1978
This notice, issued by the Women's Action Collective (WAC), was intended to mobilize abortion rights activists in coordination with the National Abortion Rights Action League to counterprotest a fundraising walk by Columbus [Ohio] Right to Life, an ...
Women's Action Collective
core  

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Collective Action-A Challenge and an Opportunity for Water Governance [PDF]

open access: yes
This paper addresses the motivations that drive participation in groups concerning water protection and provides a review of the key role collective action plays in accessing and managing water resources. It also analyses the conditions and factors which
Maria Manuela Castro Silva
core  

If it matters for the group then it matters to me: Collective action outcomes for seasoned activists. [PDF]

open access: yes, 2011
The present article reports a longitudinal study of the psychological antecedents for, and outcomes of, collective action for a community sample of activists.
Blackwood, Leda M.   +5 more
core   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Ecosystem services, social interdependencies, and collective action: a conceptual framework

open access: yes, 2018
The governance of ecosystem services (ES) has been predominantly thought of in terms of market or state-based instruments. Comparatively, collective action mechanisms have rarely been considered.
C. Barnaud   +16 more
semanticscholar   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Collective action and vulnerability: Burial societies in rural Ethiopia [PDF]

open access: yes
"Collective action can help individuals, groups, and communities achieve common goals, thus contributing to poverty reduction. Drawing on longitudinal household and qualitative community data, the authors examine the impact of shocks on household living ...
Hoddinott, John   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

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