Results 101 to 110 of about 3,971,747 (262)

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

open access: yesMolecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim   +3 more
wiley   +1 more source

Collective Action Theory: the Political Dimension

open access: yesRUDN Journal of Political Science, 2011
The article is devoted to the analysis of the modern collective action theory as one of the main analytic structures dedicated to the civil society functioning.
D B Kazarinova
doaj  

Women's Action Collective statements of philosophy and organizational purpose

open access: yes, 1974
This document, which contained the Women’s Action Collective’s (WAC) Statement of Philosophy and Statement of Organizational Purpose, outlined the WAC’s ideological foundations and system of beliefs as of May 21, 1974.
Women's Action Collective
core  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Intergroup contact, outgroup knowledge and advantaged group collective action: can who you know and what you know promote social change?

open access: yesFrontiers in Social Psychology
Some groups in society unjustly hold greater social, economic, and political power over others, placing some groups in more advantaged and others in more disadvantaged positions.
Caitlin Ferry   +4 more
doaj   +1 more source

Collective action and property rights for sustainable development

open access: yes, 2021
Institutions for collective action and systems of property rights shape how people use natural resources. These patterns of use in turn affect the outcomes of people’s agricultural production systems.
CGIAR Program on Collective Action and Property Rights (CAPRi)
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

open access: yesMolecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq   +8 more
wiley   +1 more source

Everyday forms of collective action in Bangladesh: Learning from Fifteen Cases [PDF]

open access: yes
"This paper examines fifteen cases of collective action in six villages in rural Bangladesh. Collective action was defined broadly and identified from significant episodes in previous life-history research in the same villages.
Davis, Peter
core  

Epigenetic silencing of the liver‐specific lncRNA LUNAR promotes liver cancer progression via NOTCH activation

open access: yesMolecular Oncology, EarlyView.
LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang   +9 more
wiley   +1 more source

Collective action for small-scale producers of agricultural biodiversity products: [PDF]

open access: yes
"The role of well-functioning markets for development is now widely recognized, however the challenge remains to make these markets benefit the poor and the environment.
Kruijssen, Froukje   +2 more
core  

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