Results 81 to 90 of about 3,971,747 (262)

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

open access: yesFEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos   +9 more
wiley   +1 more source

Understanding collective action

open access: yes
Collective action can be understood as an action or series of actions taken by a group of individuals to achieve common interests. It can be voluntary for some or obligatory for others, such as compulsory membership in water users' associations.
CGIAR Program on Collective Action and Property Rights
core   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Women's Action Collective Abortion Task Force counterprotest notice

open access: yes, 1978
This notice, issued by the Women's Action Collective (WAC), was intended to mobilize abortion rights activists in coordination with the National Abortion Rights Action League to counterprotest a fundraising walk by Columbus [Ohio] Right to Life, an ...
Women's Action Collective
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Collective Action in Plant Breeding [PDF]

open access: yes
Olson (1965) formulated a "Logic of Collective Action". We investigate whether a logic of collective action in plant breeding - and research and development generally - can be constructed. Using a case study on the Latin American Fund for Irrigated Rice (
Binenbaum, Eran, Pardey, Philip G.
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Collective Action-A Challenge and an Opportunity for Water Governance [PDF]

open access: yes
This paper addresses the motivations that drive participation in groups concerning water protection and provides a review of the key role collective action plays in accessing and managing water resources. It also analyses the conditions and factors which
Maria Manuela Castro Silva
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Women's Action Collective '1st Annual Famous Feminist Day' poster

open access: yes, 1977
This poster advertised a fundraising benefit held by the Women's Action Collective (WAC) in Columbus, Ohio on December 3, 1977. It billed as "the 1st Annual Famous Feminist Day" and was set in honor of Alice Paul (1885-1977), an influential suffragette ...
Women's Action Collective
core  

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