Results 41 to 50 of about 3,971,747 (262)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Unplanned Coordination: Ensemble Improvisation as Collective Action
Journal of Social Ontology, 2022 The characteristic features of ensemble dance improvisation (EDI) make it an interesting case for theories of intentional collective action. These features include the high degree of freedom enjoyed by each individual, and the lack of fixed hierarchical
Ali Hasan, Jennifer Kayle
doaj
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
COMPLEX COLLECTIVE DUTIES & ACTION-GUIDANCE
KriterionWe can often find in the literature (both popular and academic) ascriptions of complex collective duties to extensive unstructured collections of individuals.
Cristian Rettig
doaj +1 more source
Grass Roots Collective Action: Agricultural Opportunities
Journal of Agricultural and Resource Economics, 1997 Agroenvironmental problems (e.g., contamination of ground- and surface water, feed lot odors, endangered species) often involve goods and activities with public goods attributes.
Harry W. Ayer
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Women's Collective Action: Unlocking the potential of agricultural markets [PDF]
, 2013 Development actors are increasingly prioritising 'investing in women' to ensure food security and sustainability -- as well as equity -- in agricultural development.
Baden, Sally, Sally Baden
core +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Women's Action Collective information pamphlet
, 1975 This informational pamphlet from the Fall of 1975 provided a description of the Women’s Action Collective (WAC) in Columbus, Ohio, as well as brief overviews of each of the WAC’s constituent organizations.
Women's Action Collective
core