Results 41 to 50 of about 1,687,944 (295)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Trends in hepatitis C virus seroprevalence and associated risk factors among msm in Pakistan: insights from a community-based study

open access: yesScientific Reports
Pakistan bears a substantial burden of hepatitis C virus (HCV) infection, with the second-highest prevalence globally. This community-based cross-sectional study, conducted from January to December 2022 in Punjab, Pakistan, investigates the ...
Raza Tirmizi   +2 more
doaj   +1 more source

Psychological Determinants of Collective Action for Climate Justice: Insights From Semi-Structured Interviews and Content Analysis

open access: yesFrontiers in Psychology, 2021
Student initiatives for climate justice are driving forces in the climate change debate, but the psychological determinants of students’ engagement for climate justice have hardly been investigated so far.
Hannah Bührle   +2 more
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Hope and Anger as Mediators Between Collective Action Frames and Participation in Collective Mobilization: The Case of 15-M

open access: yesJournal of Social and Political Psychology, 2017
The study set out to integrate collective action models and emphasize the role of emotions. Whereas the importance of anger is indisputable, relatively little attention has been paid to the role of positive emotions, such as hope, in collective action ...
Anna Wlodarczyk   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Mobilising IDEAS in the COVID-19 Pandemic: Anti-Lockdown Actions and the Identity-Deprivation-Efficacy-Action-Subjective Well-Being Model

open access: yesJournal of Social and Political Psychology, 2023
We tested how well the Identity-Deprivation-Efficacy-Action-Subjective-wellbeing (IDEAS) model predicts citizens’ intentions to engage in collective action opposing their government, and their subjective well-being.
Fanny Lalot   +3 more
doaj   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Modes of Collective Action in Village Economies: Evidence from Natural and Artefactual Field Experiments in a Developing Country [PDF]

open access: yesAsian Development Review, 2013
In a canonical model of collective action, individual contribution to collective action is negatively correlated with group size. Yet, empirical evidence on the group size effect has been mixed, partly due to heterogeneities in group activities.
Yasuyuki Sawada   +4 more
doaj   +1 more source

Collective action problems posed by no-take zones [PDF]

open access: yes, 2006
Around 0.04% of the world's marine area is presently designated as no-take zone (NTZ), in which all fishing is banned. The IUCN, backed by many marine fisheries and ecology scientists, has called for this to be increased to 20-30% by 2012 in order to ...
Jones, PJS
core   +1 more source

Home - About - Disclaimer - Privacy