Results 71 to 80 of about 1,673,869 (274)
Molecular Oncology, EarlyView.A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath +13 more
wiley +1 more source
Collective action and rationality models
Estudios Fronterizos, 2004 The Olsonian theory of collective action (Olson, 1965) assumes a model of economic rationality, based on a simple calculus between costs and benefits, that can be hardly hold at present, given the models of rationality proposed recently by several fields
Luis Miguel Miller Moya
doaj
Being Positively Moved by Climate Protest Predicts Peaceful Collective Action
Global Environmental PsychologyPeople can be motivated to engage in collective action for climate protection because they are angry about an injustice or because they are emotionally moved by the idea that they can achieve something together. However, previous research on emotions and
Helen Landmann, Jascha Naumann
doaj +1 more source
Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids
Molecular Oncology, EarlyView.This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici +8 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Collective action to secure property rights for the poor: A case study in Jambi Province, Indonesia [PDF]
"This study presents an approach to analyzing decentralized forestry and natural resource management and land property rights issues, and catalyzing collective action among villages and district governments.
Colfer, Carol J. Pierce +6 more
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International support for the Arab uprisings: Understanding sympathetic collective action using theories of social dominance and social identity [PDF]
, 2015 Inspired by the popular Arab protests against oppressive regimes that began in 2010, people around the world protested in sympathy with the Arab peoples.
Aiello, Antonio +16 more
core +3 more sources
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Can the Twain Ever Meet? Environmental Jurisprudence and Justice in India
Ecology, Economy and Society – The INSEE Journal, 2020 Manshi Asher
doaj +1 more source
Inequality, Coalitions and Collective Action [PDF]
In a model where cooperation is beneficial, but subject to cheating, and is supported by trigger strategy punishments in a repeated game, we explore the relationship between the nature of cooperation (size and composition of coalitions) and underlying ...
Nirvikar Singh, Pranab K. Bardhan
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