Results 71 to 80 of about 1,692,148 (291)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Strengthening collective action [PDF]

open access: yes
This brief reviews how citizens, nongovernmental organizations (NGOs), government agencies, and others can strengthen collective action. The authors discuss ways of facilitating collective action, of redesigning institutions and incentives and of the ...
Bruns, Bryan Randolph   +1 more
core  

Collective action and rationality models

open access: yesEstudios Fronterizos, 2004
The Olsonian theory of collective action (Olson, 1965) assumes a model of economic rationality, based on a simple calculus between costs and benefits, that can be hardly hold at present, given the models of rationality proposed recently by several fields
Luis Miguel Miller Moya
doaj  

Being Positively Moved by Climate Protest Predicts Peaceful Collective Action

open access: yesGlobal Environmental Psychology
People can be motivated to engage in collective action for climate protection because they are angry about an injustice or because they are emotionally moved by the idea that they can achieve something together. However, previous research on emotions and
Helen Landmann, Jascha Naumann
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

open access: yesMolecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon   +4 more
wiley   +1 more source

Inequality, Coalitions and Collective Action [PDF]

open access: yes
In a model where cooperation is beneficial, but subject to cheating, and is supported by trigger strategy punishments in a repeated game, we explore the relationship between the nature of cooperation (size and composition of coalitions) and underlying ...
Nirvikar Singh, Pranab K. Bardhan
core  

Can the Twain Ever Meet? Environmental Jurisprudence and Justice in India

open access: yesEcology, Economy and Society – The INSEE Journal, 2020
Manshi Asher
doaj   +1 more source

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