Results 101 to 110 of about 1,036,630 (289)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Collective excitations in liquid DMSO : FIR spectrum, Low frequency vibrational density of states and ultrafast dipolar solvation dynamics

open access: yes, 2016
Valuable dynamical and structural information about neat liquid DMSO at ambient conditions can be obtained through study of low frequency vibrations in the far infrared (FIR), that is, terahertz regime.
Bagchi, Biman, Hazra, Milan
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Legal Issues of Conducting Collective Bargaining as a Form of Social Partnership

open access: yesСибирское юридическое обозрение
This article addresses problematic aspects of collective bargaining as the principal form of social partnership. It is noted that the linguistic meaning of the term, which emphasises communication between multiple actors, does not allow identification of
V. A. Safonov
doaj   +1 more source

The collective labour agreement as a key tool for driving corporate social responsibility: banking sector analysis

open access: yesManagement Letters/Cuadernos de Gestión, 2017
In this paper we focus on the role of the human resources department, specifically in the area of labour relations, analysing how collective bargaining and collective agreement can be key mechanisms for the development of corporate social responsibility (
José María Biedma Ferrer   +2 more
doaj   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

open access: yesMolecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

Particularități ale dialogului social în cadrul autorităților și instituțiilor publice

open access: yesRevista Transilvană de Ştiinţe Administrative, 2010
Dialogue is considered to be the opposite of rhetoric. This is true, especially when it comes to social dialogue, meant to prevent conflicts and to ensure social peace. But is social peace a goal? And which are its particularities when it comes to public
Raluca DIMITRIU
doaj  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Light-driven liquid crystalline nonlinear oscillator under optical periodic forcing

open access: yes, 2007
An all-optically driven strategy to govern a liquid crystalline collective molecular nonlinear oscillator is discussed. It does not require external feedbacks of any kind while the oscillator and a time-depending perturbation both are sustained by ...
A. Pikovsky   +5 more
core   +2 more sources

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