Results 41 to 50 of about 58,996 (261)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Individual monitoring of occupational external radiation in radiation workers of medical institutions in Jing’an District, Shanghai

Shanghai yufang yixue
ObjectiveTo analyze the individual monitoring results of the radiation workers in Shanghai’s Jing’an District from 2017 to 2023, to assess the occupational protection status as well as to offer scientific references for enhancing occupational health and ...
KUANG Yujie, XIAO Hong, GAO Linfeng, WANG Bin, LU Shunqi   +4 more
doaj   +1 more source

Effect of X-ray scan quality on the collective effective dose in patients in telemedicine [PDF]

Digital Diagnostics
BACKGROUND: The key objective of a healthcare provider is to ensure the quality and increase the efficiency of X-ray diagnostics in both municipal and private medical facilities. A poor-quality radiologic image requires repeated procedures, which results
Zoya A. Lantukh, Daria D. Kozhikhina, Kirill V. Tolkachev, Maria P. Shatenok, Ilya V. Soldatov, Uliya V. Druzhinina, Yuriy A. Vasilev, Sergey A. Ryzhov, Aleksandr V. Vodovatov   +8 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Trends in diagnostic nuclear medicine in Sweden (2008–2023): utilisation, radiation dose, and methodological insights

EJNMMI Physics
Background Diagnostic imaging is a dynamic medical field. In nuclear medicine, advancements introduce new procedures utilising innovative radiopharmaceuticals.
Anja Almén
doaj   +1 more source

Effect of Exposure to Ionizing Radiation on Biomarker of Oxidative Damage of DNA

بهداشت و ایمنی کار, 2021
Introduction: one of the most important complications of exposure to ionizing radiation is emergence of cancer tumors, which happens as a result of oxidative DNA.
Farhad Forouharmajd, Azam Salehi, Karim Ebrahimpour   +2 more
doaj  

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Evaluation of radiation dose to Korean population by general radiography

Nuclear Engineering and Technology
General radiography has the highest usage among diagnostic radiology in Korea, resulting in high radiation dose by general radiography. For the medical radiation safety of patients, it is necessary to evaluate Korean population dose by general ...
Hyung Woo Nam, Min Woo Kwak, Shin Dong Lee, Ju Young Kim, Kwang Pyo Kim   +4 more
doaj   +1 more source

Celebrate the power of imaging: the european day of radiology

Journal of the Belgian Society of Radiology, 2011
Approximately 1.800.000 CT examinations are performed every year in Belgium. With a mean dose 0,5 mSv, the annual collective dose from CT could induce up to 450 cancer. This number has to be compared to the 45 000 observed new cancers yearly.
D Tack
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source