Results 111 to 120 of about 8,267,972 (303)

An approach for rapid establishment of patient effective dose during radiology and results for two large university hospitals

, 2000
Patient dosimetry and assessment of effective dose was implemented under the condition that measurements involve commonly available instrumentation. Four categories of examination were distinguished: radiographs with manual techniques, radiographs with ...
Kamman, RL, Berting, R, van der Brink, HA, Geleijns, J   +3 more
core  

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Youth Research Collective Life Patterns Project - Cohort 2

Life Patterns is an Australian Research Council funded project following the lives of young Australians since the 1990s. The project has followed two cohorts of young Australians during the last 30 years: Cohort 1 who were aged 18 in 1991 and Cohort 2 ...
Youth Research Collective
core   +1 more source

OEDIPE, a software for personalized Monte Carlo dosimetry and treatment planning optimization in nuclear medicine: absorbed dose and biologically effective dose considerations

, 2014
For targeted radionuclide therapies, treatment planning usually consists of the administration of standard activities without accounting for the patient-specific activity distribution, pharmacokinetics and dosimetry to organs at risk.
A. Desbrée, C. de Labriolle Vaylet, A. Petitguillaume, D. Franck, M. Bernardini, Desbreé, A., Bernardini, M., Franck, D., D. Broggio, Broggio, D., Petitguillaume, A., de Labriolle Vaylet, C.   +11 more
core   +1 more source

Optimal designs for estimating critical effective dose under model uncertainty in a dose response study [PDF]

Toxicologists have been increasingly using a class of models to describe a continuous response in the last few years. This class consists of nested nonlinear models and is used for estimating various parameters in the models or some meaningful function ...
Shpilev, Piter, Dette, Holger, Wong, Weng Kee, Pepelyshev, Andrey   +3 more
core   +2 more sources

Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy

Molecular Oncology, EarlyView.
We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen, Zhi Zhao, Henrik Horndalsveen, Maria Moksnes Bjaanæs, Bjørn Henning Grønberg, Tarje Halvorsen, Tesfaye Madebo, Marianne Aanerud, Jussi Koivunen, Kersti Oselin, Saulius Cicenas, Nina Helbekkmo, Jarkko Ahvonen, Maria Silvoniemi, Tine Norman Alver, Tonje Dalen, Åsa Kristina Öjlert, Saima Jamil Farooqi, Åslaug Helland, Vilde Drageset Haakensen   +19 more
wiley   +1 more source

A role for eIF5A in translational control of stress‐inducible proteins in multiple myeloma cell lines

Molecular Oncology, EarlyView.
Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both, Ingrid A. M. Derks, Raphaël Vanleyssem, Marine Leclercq, Najla El Hachem, Pierre Close, Eric Eldering, Marco Vincent Haselager   +7 more
wiley   +1 more source

Problems of verification of information on medical exposure doses in Form No. 3-DOZ and suggestion for their solution

Радиационная гигиена
The article analyzes the data of the federal state statistical observation form No. 3-DOZ for 2022-2023, which revealed a significant increase in medical radiation doses to patients in the Russian Federation, especially in Khabarovsk Krai. The purpose of
A. V. Vodovatov, E. A. Kosarlukova, A. M. Biblin, R. R. Akhmatdinov, N. M. Vishnyakova   +4 more
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Youth Research Collective Life Patterns Project - Cohort 1

Life Patterns is an Australian Research Council funded project following the lives of young Australians since the 1990s. The project has followed two cohorts of young Australians during the last 30 years: Cohort 1 who were aged 18 in 1991 and Cohort 2 ...
Youth Research Collective
core   +1 more source