Results 91 to 100 of about 8,267,972 (303)
Introduction of software for patient dose assessment in computed tomography
Vietnam Journal of Science, Technology and EngineeringIn recent years, there has been increasing concern about the radiation dose to patients undergoing radiological examinations, particularly computed tomography (CT), which has been reported to contribute the highest collective dose among X-ray diagnostic
Nhu Tuyen Pham +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
A note on nonparametric estimation of the effective dose in quantal bioassay [PDF]
For the common binary response model we propose a direct method for the nonparametric estimation of the effective dose level ED? (0Binary response model,effective dose level,nonparametric regression,isotonic regression,order restricted inference,local ...
Dette, Holger +2 more
core
, 2012 Medidas da radiação gama ambiental foram feitas em algumas regiões da cidade de Ribeirão Preto-SP, de forma a contribuir para o conhecimento acerca dos níveis desse tipo de radiação no estado de São Paulo e no território brasileiro.
Cavalcante, Fernanda +1 more
core +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Practical considerations for optimal designs in clinical dose finding studies [PDF]
Determining an adequate dose level for a drug and, more broadly, characterizing its dose response relationship, are key objectives in the clinical development of any medicinal drug. If the dose is set too high, safety and tolerability problems are likely
Dette, Holger +2 more
core
Limites de la notion de dose collective
, 1981 La dose collective, notion apparue en radioprotection vers la fin des années 1960, a rendu de grands services au plan opérationnel, permettant à la fois de faire des bilans de doses ponctuels ou globaux et de faire des choix technologiques en vue d ...
G. Wolber, S. Vignes, M. Bertin
core +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Радиационная гигиена, 2015 The article presents the outcomes of the generalized analysis of personnel, patients and population radiation doses information obtained from the Unified System of Individual Dose Control (USIDC) for 2014.
V. S. Repin +12 more
doaj
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source