Results 81 to 90 of about 8,267,972 (303)

Immunomodulatory properties and molecular effects in inflammatory diseases of low-dose X-irradiation [PDF]

, 2012
Inflammatory diseases are the result of complex and pathologically unbalanced multicellular interactions. For decades, low-dose X-irradiation therapy (LD-RT) has been clinically documented to exert an anti-inflammatory effect on benign diseases and ...
Seegenschmiedt, Michael H., Keilholz, Ludwig, Stephanie Hehlgans, M. Heinrich eSeegenschmiedt, Guido Hildebrandt, Gaipl, Udo Sebastian, Udo S. Gaipl, Rödel, Franz, Hehlgans, Stephanie, Udo S Gaipl, Manda, Katrin, Ludwig eKeilholz, M. Heinrich Seegenschmiedt, Guido eHildebrandt, Hildebrandt, Guido, Benjamin eFrey, Franz eRödel, Ludwig Keilholz, Frey, Benjamin, Benjamin Frey, Rödel, Claus, Katrin Manda, Claus Rödel, Stephanie eHehlgans, Franz Rödel, Claus eRödel, Katrin eManda   +26 more
core   +1 more source

Dynamics of medical exposure of the population of the Rostov region for the period 2019-2024

Радиационная гигиена
The contribution of medical exposure to the collective effective dose is increasing both in the Russian Federation and in the Rostov Region, as confirmed by the results of the annual radiation-hygienic passportization.   The objective of this study is to
M. V. Kalinina, T. B. Namatyan, E. V. Kovalev, T. V. Zhukova, S. A. Musienko, A. B. Namatyan   +5 more
doaj   +1 more source

Análise dos registros de dose ocupacional externa no Brasil

Brazilian Journal of Radiation Sciences, 2015
Brazil, a continental country, with actually more than 150,000 workers under individual monitoring for ionizing radiation, has implemented in 1987 a centralized system for storage of external occupational dose.
Claudia Lucia de Pinho Mauricio, Herica Luiza Ramos da Silva, Claudio Ribeiro da Silva   +2 more
doaj   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma

FEBS Letters, EarlyView.
Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos, Antonia Petropoulou, Alexandra Anastogianni, Angelina Bania, Vassilis Stamatakis, Argyris Alexiou, Chi‐Ping Day, Glenn Merlino, Katerina Grafanaki, Constantinos Stathopoulos   +9 more
wiley   +1 more source

MANAGEMENT OF SPECIAL RADIOACTIVE WASTES: PRACTICAL ADVANCES AND CURRENT CHALLENGES

Радиационная гигиена, 2015
The article covers methodological approaches for substantiating the assignment of radioactive wastes (RAO) to special radioactive wastes, as well as the results of its practical application within initial registration of RAO.
I. I. Linge, M. N. Savkin, M. V. Vedernikova   +2 more
doaj  

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Collective dose IRSN view on its indications and contraindications

, 2002
The concept of collective protection appeared in 1959 in the first report of the international commission on Radiological Protection (ICRP). During the course of the next decades, ICRP gave details on the use of collective dose, in particular on its role
Supervil, S
core  

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source