Results 71 to 80 of about 8,267,972 (303)

High dose rate brachytherapy as monotherapy for localised prostate cancer : a hypofractionated two-implant approach in 351 consecutive patients [PDF]

, 2013
BACKGROUND: To report the clinical outcome of high dose rate brachytherapy as sole treatment for clinically localised prostate cancer. METHODS: Between March 2004 and January 2008, a total of 351 consecutive patients with clinically localised prostate ...
Markus Ratka, Milickovic, Natasa, Nikolaos Zamboglou, Dimos Baltas, Zamboglou, Nikolaos, Ratka, Markus, Natasa Milickovic, Chatzikonstantinou, Georgios, Tunn, Ulf W., Baltas, Dimos, Tselis, Nikolaos, Georgios Chatzikonstantinou, Nikolaos Tselis, Ulf W Tunn   +13 more
core   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Dose assessment due to terrestrial gamma radiation in Ibadan, South Western Nigeria

, 2003
The activities of primordial radionuclides in surface soil at Ibadan, South-Western Nigeria have been measured with a 7.6cm x 7.6cm NaI(TL) detector.
Farai, I.P., Arogunjo, A.M.
core   +1 more source

Dose and number of applications that maximise fungicide effective life exemplified by Zymoseptoria tritici on wheat - a model analysis [PDF]

, 2016
Two key decisions that need to be taken about a fungicide treatment programme are (i) the number of applications that should be used per crop growing season, and (ii) the dosage that should be used in each application.
Van Den Berg, F., Van Den Bosch, F., Paveley, N. D., Vandenbosch, Frank, Van Den Berg, Femke   +4 more
core   +1 more source

Medical irradiation risk assessment based on the data of radiation-hygienic passportization in the regions of the Russian Federation

Радиационная гигиена, 2016
This article is aimed at methodology development for collective risk assessment of medical irradiation, basing on results of radiation-hygienic passportization in the Russian Federation regions, i.e.
V. Ju. Golikov
doaj  

Analysis of medical exposure levels of the Russian Federation population in 2023 using the updated form No. 3–DOZ

Радиационная гигиена
Introduction: To successfully address the challenges of optimizing radiation protection during medical exposure, it is essential to have information on patient exposure levels and the structure of diagnostic radiology in medical organizations across the ...
A. V. Vodovatov, E. A. Kosarlukova, A. M. Biblin, R. R. Akhmatdinov, A. A. Bratilova   +4 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Dose calculations for [¹³¹I] meta-iodobenzylguanidine-induced bystander effects

, 2014
Targeted radiotherapy is a potentially useful treatment for some cancers and may be potentiated by bystander effects. However, without estimation of absorbed dose, it is difficult to compare the effects with conventional external radiation treatment ...
R. J. Mairs, Seymour, C B, M. D. Gow, Mairs, R J, C. B. Seymour, Gow, M.D., Mothersill, C.E., Seymour, C.B., C. E. Mothersill, Mairs, R.J., M. Boyd, W. V. Prestiwch, Mothersill, C E, Prestiwch, W V, Prestiwch, W.V., Boyd, Marie, Boyd, M., Gow, M D   +17 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source