Results 91 to 100 of about 232,783 (214)

Foresight, Partnerships, and Cross Sector Collective Impact: Strategies to Build A Partnership World

open access: yesInterdisciplinary Journal of Partnership Studies
This article discusses the value of connecting foresight leadership with partnership practice to achieve cross-sector collective impacts. The dimensions of future consciousness and foresight literacy are described.
Daniel Pesut
doaj   +1 more source

Generating change through collective impact and systems science for childhood obesity prevention: The GenR8 Change case study. [PDF]

open access: yesPLoS One, 2022
Bolton KA   +11 more
europepmc   +1 more source

Characterization of therapeutic antibodies targeting lymphatic and vascular resistance factor for the treatment of hypervascularized and highly metastatic cancers

open access: yesMolecular Oncology, EarlyView.
LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David   +12 more
wiley   +1 more source

Mental Health Stigma Reduction in the Midwestern United States: Evidence from a Digital Campaign Using a Collective Impact Model. [PDF]

open access: yesJ Community Health, 2022
Diouf F   +8 more
europepmc   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Collective Expression of Persipa Pati Football Supporters Fanaticm Through the “Diurus Cah-Cah” Movement

open access: yesActive: journal of physical education, sport, health and recreation
This study examines the collective expression of fanaticism of Persipa Pati supporters through the "Diurus Cah-Cah" movement. Research problems include how forms of collective fanaticism are formed, the driving factors for the emergence of movements ...
Mareno Andrian Winanda, Mugiyo Hartono
doaj   +1 more source

USP7 inhibits FOXO1 activity in chronic lymphocytic leukaemia cells enhancing cell survival

open access: yesMolecular Oncology, EarlyView.
CLL cells rely on BCR‐mediated signalling for survival and proliferation in part through suppression of FOXO1. FOXO1 activity is regulated by a plethora of post‐translational modifications including phosphorylation and ubiquitination. We demonstrated that dual inhibition of BCR signalling and the deubiquitinase USP7 activates FOXO1, modulating its ...
Hassan N.B. Almuhanna   +8 more
wiley   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

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